CARM1 抗体
Quick Overview for CARM1 抗体 (ABIN969002)
抗原
See all CARM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CARM1 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human CARM1 expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Dual role of the arginine methyltransferase CARM1 in the regulation of c-Fos target genes." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 22, Issue 9, pp. 3337-47, (2008) (PubMed).
: "The protein arginine methyltransferases CARM1 and PRMT1 cooperate in gene regulation." in: Nucleic acids research, Vol. 36, Issue 10, pp. 3202-13, (2008) (PubMed).
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: "Dual role of the arginine methyltransferase CARM1 in the regulation of c-Fos target genes." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 22, Issue 9, pp. 3337-47, (2008) (PubMed).
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- CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))
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别名
- CARM1
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背景
- Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in signal transduction, metabolism of nascent pre-RNA, and transcriptional activation (Frankel et al. 2002 (PubMed 11724789). Tissue specificity: Overexpressed in prostate adenocarcinomas and high-grade prostatic intraepithelial neoplasia.
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分子量
- 65 kDa
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UniProt
- Q86X55
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of fat Cell Differentiation
抗原
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