电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

BLK 抗体

This anti-BLK antibody is a 小鼠 单克隆 antibody detecting BLK in ELISA 和 IHC. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN968980
发货至: 中国

Quick Overview for BLK 抗体 (ABIN968980)

抗原

See all BLK 抗体
BLK (B Lymphoid Tyrosine Kinase (BLK))

适用

  • 66
  • 24
  • 15
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 53
  • 10
  • 1
小鼠

克隆类型

  • 55
  • 11
单克隆

标记

  • 39
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BLK antibody is un-conjugated

应用范围

  • 51
  • 34
  • 28
  • 13
  • 13
  • 7
  • 6
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
ELISA, Immunohistochemistry (IHC)

克隆位点

9D10D1
  • 原理

    BLK Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of BLK expressed in E. Coli.

    亚型

    IgG2a
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Tretter, Ross, Dordai, Desiderio: "Mimicry of pre-B cell receptor signaling by activation of the tyrosine kinase Blk." in: The Journal of experimental medicine, Vol. 198, Issue 12, pp. 1863-73, (2003) (PubMed).

  • 抗原

    BLK (B Lymphoid Tyrosine Kinase (BLK))

    别名

    BLK

    背景

    BLK ( B lymphoid tyrosine kinase), with 505-amino acid protein (about 56KDa), belongs to the Src non-receptor tyrosine kinases family.Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization, and membrane trafficking.Blk is expressed exclusively by B lymphocytes and it is thought to function in a signal transductory pathway specific to this lineage. B lymphoid expression of an active Blk mutant caused proliferation of B progenitor cells and enhanced responsiveness of these cells to interleukin 7. Thus, sustained activation of Blk induces responses normally associated with the pre-BCR.

    UniProt

    P51451

    途径

    Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
You are here:
Chat with us!