电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

APOB 抗体

Cited in 2+ publications. The 小鼠 单克隆 anti-APOB antibody (Clone 6G6) (ABIN968961) specifically detects APOB in ICC, ELISA 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN968961
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for APOB 抗体 (ABIN968961)

抗原

See all APOB 抗体
APOB (Apolipoprotein B (APOB))

适用

  • 114
  • 27
  • 26
  • 6
  • 2

宿主

  • 80
  • 45
  • 14
  • 2
  • 2
小鼠

克隆类型

  • 84
  • 58
单克隆

标记

  • 60
  • 24
  • 15
  • 7
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This APOB antibody is un-conjugated

应用范围

  • 86
  • 46
  • 41
  • 30
  • 30
  • 18
  • 17
  • 9
  • 7
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Immunocytochemistry (ICC), ELISA, Flow Cytometry (FACS)

克隆位点

6G6
  • 原理

    ApoB Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human ApoB expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Benn: "Apolipoprotein B levels, APOB alleles, and risk of ischemic cardiovascular disease in the general population, a review." in: Atherosclerosis, Vol. 206, Issue 1, pp. 17-30, (2009) (PubMed).

    Peterson, Mack, Hall, Alsup, Alexander, Sully, Sawires, Cheung, Otto, Gresham: "Apolipoprotein B Is an innate barrier against invasive Staphylococcus aureus infection." in: Cell host & microbe, Vol. 4, Issue 6, pp. 555-66, (2008) (PubMed).

  • 抗原

    APOB (Apolipoprotein B (APOB))

    别名

    ApoB

    背景

    This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.

    分子量

    516 kDa

    基因ID

    338

    UniProt

    P04114

    途径

    Lipid Metabolism
You are here: