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MAP1B 抗体 (AA 1745-1858)

MAP1B 适用: 人, 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal 6-MAP1B unconjugated
产品编号 ABIN968911
发货至: 中国
  • 抗原 See all MAP1B 抗体
    MAP1B (Microtubule-Associated Protein 1B (MAP1B))
    抗原表位
    • 16
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1745-1858
    适用
    • 29
    • 23
    • 23
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 29
    • 1
    小鼠
    克隆类型
    • 29
    • 1
    单克隆
    标记
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAP1B antibody is un-conjugated
    应用范围
    • 14
    • 13
    • 13
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    Western Blotting (WB)
    交叉反应
    人, 大鼠
    产品特性
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Mouse MAP1B aa. 1745-1858
    克隆位点
    6-MAP1B
    亚型
    IgG2a
    Top Product
    Discover our top product MAP1B Primary Antibody
  • 说明

    Related Products: ABIN967389

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    250 μg/mL
    缓冲液
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store undiluted at -20° C.
  • Ma, Himes, Shea, Fischer: "Axonal transport of microtubule-associated protein 1B (MAP1B) in the sciatic nerve of adult rat: distinct transport rates of different isoforms." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 20, Issue 6, pp. 2112-20, (2000) (PubMed).

    Tögel, Wiche, Propst: "Novel features of the light chain of microtubule-associated protein MAP1B: microtubule stabilization, self interaction, actin filament binding, and regulation by the heavy chain." in: The Journal of cell biology, Vol. 143, Issue 3, pp. 695-707, (1998) (PubMed).

  • 抗原
    MAP1B (Microtubule-Associated Protein 1B (MAP1B))
    别名
    MAP1B (MAP1B 产品)
    别名
    FUTSCH antibody, MAP5 antibody, Mtap1b antibody, A230055D22 antibody, AI843217 antibody, LC1 antibody, Mtap-5 antibody, Mtap5 antibody, microtubule associated protein 1B antibody, microtubule-associated protein 1B antibody, MAP1B antibody, Map1b antibody
    背景
    Microtubule-associated proteins (MAPs) play a crucial role in the development and structure of nerve cells. These proteins are important for the assembly and stability of microtubles during neurite outgrowth and for the morphology of neuronal processes, such as dendrites. MAP1B encodes for a single precursor protein that is cleaved to produce a single heavy chain of 280 kDa and a light chain of 32 kDa which become noncovalently associated. Expression levels of MAP1B are reportedly highest in the brain and are modulated during development as reported with gene silencing experiments that implicate MAP1B's role during neuronal differentiation. In addition, MAP1B can be selectively phosphorylated depending on the cell type, subcellular localization and developmental phase. In neurons, MAP1B is expressed as a glycoprotein at the plasma membrane, where it can interact with proteins participating in axonal guiding. MAP1B has been reported to be observable to migrate in a range between 320-340 kDa. This antibody is routinely tested by western blot analysis.
    分子量
    320-340 kDa
    途径
    Microtubule Dynamics, Regulation of Cell Size
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