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HNF1B 抗体 (AA 1-101)

Name: HNF1B 抗体 (AA 1-101)
SKU: ABIN968855
Availability: OutOfStock

This anti-HNF1B antibody is a 小鼠单克隆 antibody detecting HNF1B in WB 和 IF. Suitable for 人, 大鼠, 小鼠和犬. This Primary Antibody has been cited in 3+ publications.

Western Blotting (WB) image for anti-HNF1 Homeobox B (HNF1B) (AA 1-101) antibody (ABIN968855) (HNF1B 抗体 (AA 1-101))

Western blot analysis of HNF-1beta on a rat kidney lysate. (HNF1B 抗体 (AA 1-101))

Immunofluorescence staining of normal rat kidney. (HNF1B 抗体 (AA 1-101))

3 images

(3 references)

产品编号 ABIN968855

发货至: 中国

Quick Overview for HNF1B 抗体 (AA 1-101) (ABIN968855)

抗原

See all HNF1B 抗体

HNF1B (HNF1 Homeobox B (HNF1B))

适用

人, 大鼠, 小鼠, 犬

宿主

小鼠

克隆类型

单克隆

标记

This HNF1B antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF)

克隆位点

25-HNF

Discover our top product HNF1B Primary Antibody

抗原表位
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AA 1-101

交叉反应

大鼠, 人, 犬

产品特性

1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

纯化方法

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

免疫原

Mouse HNF-1beta aa. 1-101

亚型

IgG1
anti-HNF1 Homeobox B (HNF1B) (AA 29-118) antibody
HNF1B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E9 unconjugated

anti-HNF1 Homeobox B (HNF1B) (AA 29-118) antibody
HNF1B 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3H4 unconjugated

anti-HNF1 Homeobox B (HNF1B) (N-Term) antibody
HNF1B 适用: 人, 大鼠, 小鼠, 斑马鱼, 犬, Cow, 马, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated

anti-HNF1 Homeobox B (HNF1B) (AA 159-300) antibody
HNF1B 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-HNF1 Homeobox B (HNF1B) (AA 1-557) antibody
HNF1B 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-HNF1 Homeobox B (HNF1B) (AA 539-704) antibody
HNF1B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-HNF1 Homeobox B (HNF1B) (Internal Region) antibody
Verified HNF1B 适用: 人, 小鼠 WB, ELISA, ICC 宿主: 山羊 Polyclonal unconjugated

anti-HNF1 Homeobox B (HNF1B) (Internal Region) antibody
HNF1B 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-HNF1 Homeobox B (HNF1B) (AA 100-200) antibody
HNF1B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-HNF1 Homeobox B (HNF1B) (C-Term) antibody
HNF1B 适用: 人, 大鼠, 小鼠, 犬, Cow, 马, 豚鼠, 兔, 绵羊 WB 宿主: 兔 Polyclonal unconjugated

说明

Related Products: ABIN968547, ABIN967389

限制

仅限研究用
状态

Liquid

浓度

250 μg/mL

缓冲液

Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store undiluted at -20° C.
Soubt, Marksitzer, Menoud, Nagamine: "Role of tissue-specific transcription factor LFB3 in a cyclic AMP-responsive enhancer of the urokinase-type plasminogen activator gene in LLC-PK1 cells." in: Molecular and cellular biology, Vol. 18, Issue 8, pp. 4698-706, (1998) (PubMed).

Ringeisen, Rey-Campos, Yaniv: "The transactivation potential of variant hepatocyte nuclear factor 1 is modified by alternative splicing." in: The Journal of biological chemistry, Vol. 268, Issue 34, pp. 25706-11, (1994) (PubMed).

De Simone, De Magistris, Lazzaro, Gerstner, Monaci, Nicosia, Cortese: "LFB3, a heterodimer-forming homeoprotein of the LFB1 family, is expressed in specialized epithelia." in: The EMBO journal, Vol. 10, Issue 6, pp. 1435-43, (1991) (PubMed).
抗原

HNF1B (HNF1 Homeobox B (HNF1B))

别名

HNF-1beta

背景

HNF's (Hepatocyte Nuclear Factor) are POU-homeodomain-containing liver enriched transcription factors that include HNF1-alpha, HNF1-beta, HNF-3alpha, HNF-3beta, HNF-4 and HNF-6. HNF-1 is expressed in liver, kidney, and intestine, while HNF-1beta is expressed highest in kidney with lower levels in intestine, lung, and liver. Both HNF-1 and HNF-1beta have short N-terminal alpha-helical segments that facilitate homodimerization (A-domain), a region related to POU-specific A-box (B-domain), and a homeodomain (C-domain). The HNF-1 and HNF-1beta homo- and hetero-dimers transactivate genes required for development of various tissues. Both transcription factors can bind the consensus HNF1 inverted palindromic sequence GTTAATNATTAAC. HNF-1 represses its own transcription and data suggests that there is coordinate regulation between HNF-1 and HNF-4. Although HNF-4 induces HNF-1 transcription, HNF-1 downregulates HNF-4 activity by binding to the AF2 region in the activation domain of HNF-4. Thus, HNF transcription factors may be involved in various aspects of the regulation of gene transcription throughout development.
Synonyms: Hepatocyte Nuclear Factor-1beta

分子量

51 kDa

途径

Hormone Transport, Stem Cell Maintenance, Tube Formation