RUVBL2 抗体 (AA 180-228)
(3 references)-
- 抗原 See all RUVBL2 抗体
- RUVBL2 (RuvB-Like 2 (E. Coli) (RUVBL2))
-
抗原表位
- AA 180-228
-
适用
- 人, 小鼠, 大鼠, 犬, 小鸡
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This RUVBL2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 交叉反应
- 犬, 大鼠, 小鼠, 小鸡
- 产品特性
-
1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human Reptin 52/TIF-496 aa. 180-228
- 克隆位点
- 42-TIP49b
- 亚型
- IgG1
- Top Product
- Discover our top product RUVBL2 Primary Antibody
-
anti-RuvB-Like 2 (E. Coli) (RUVBL2) (AA 113-370) antibody
RUVBL2 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 1A6 unconjugated
anti-RuvB-Like 2 (E. Coli) (RUVBL2) (AA 113-370) antibodyRUVBL2 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1D9 unconjugated
anti-RuvB-Like 2 (E. Coli) (RUVBL2) (AA 1-463) antibodyRUVBL2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-RuvB-Like 2 (E. Coli) (RUVBL2) (N-Term) antibodyRUVBL2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-RuvB-Like 2 (E. Coli) (RUVBL2) (AA 304-458) antibodyRUVBL2 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RuvB-Like 2 (E. Coli) (RUVBL2) (N-Term) antibodyRUVBL2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-RuvB-Like 2 (E. Coli) (RUVBL2) (AA 281-444) antibodyRUVBL2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-RuvB-Like 2 (E. Coli) (RUVBL2) (AA 1-463) antibodyRUVBL2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C6 unconjugated
anti-RuvB-Like 2 (E. Coli) (RUVBL2) (N-Term) antibodyRUVBL2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 猴, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RuvB-Like 2 (E. Coli) (RUVBL2) (Ser129) antibodyRUVBL2 适用: 人, 小鼠, 大鼠, Cow WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20°C.
-
-
: "TIP49b, a regulator of activating transcription factor 2 response to stress and DNA damage." in: Molecular and cellular biology, Vol. 21, Issue 24, pp. 8398-413, (2001) (PubMed).
: "Pontin52 and reptin52 function as antagonistic regulators of beta-catenin signalling activity." in: The EMBO journal, Vol. 19, Issue 22, pp. 6121-30, (2000) (PubMed).
: "TIP49b, a new RuvB-like DNA helicase, is included in a complex together with another RuvB-like DNA helicase, TIP49a." in: The Journal of biological chemistry, Vol. 274, Issue 32, pp. 22437-44, (1999) (PubMed).
-
: "TIP49b, a regulator of activating transcription factor 2 response to stress and DNA damage." in: Molecular and cellular biology, Vol. 21, Issue 24, pp. 8398-413, (2001) (PubMed).
-
- 抗原
- RUVBL2 (RuvB-Like 2 (E. Coli) (RUVBL2))
- 别名
- TIP49b (RUVBL2 产品)
- 别名
- ECP51 antibody, INO80J antibody, REPTIN antibody, RVB2 antibody, TIH2 antibody, TIP48 antibody, TIP49B antibody, mp47 antibody, p47 antibody, reptin antibody, wu:fi25f01 antibody, zreptin antibody, MGC52995 antibody, tip48 antibody, xReptin antibody, rvb2 antibody, ecp51 antibody, cgi-46 antibody, tip49b antibody, MGC69398 antibody, RUVBL2 antibody, AAEL010341 antibody, Reptin antibody, rept antibody, RuvB like AAA ATPase 2 antibody, RuvB-like protein 2 antibody, RuvB-like AAA ATPase 2 antibody, RuvB like AAA ATPase 2 L homeolog antibody, ruvB-like 2 antibody, TATA box-binding protein antibody, ruvb-like 2 antibody, ruvB-like helicase 2 antibody, RUVBL2 antibody, Ruvbl2 antibody, ruvbl2 antibody, ruvbl2.L antibody, LOC726816 antibody, HBUT_RS02095 antibody, HAN_2g314 antibody, LOC100282179 antibody, LOC100284260 antibody, LOC5573243 antibody
- 背景
- Processes involving DNA transcription, replication and repair are necessary in maintaining normal cell function. For each of these processes, the double stranded NA must first be unwound. This is achieved in an ATP-dependent manner by enzymes termed DNA helicases. Reptin52/TIP49b is a DNA helicase that directly interacts with Pontin52/TIP49a. Reptin52/TIP49b and Pontin52/TIP49a belong to a family of highly conserved proteins that share homology with the bacterial protein RuvB, a helicase involved in double-strand break repair and homologous recombination. Both are TATA binding protein (TBP) interacting proteins that bind to beta-Catenin and are among the 12 polypeptides that comprise the INO80 chromatin-remodeling complex. It has also been demonstrated that Reptin52/TIP49b and Pontin52/TIP49a can be found in a complex with the proto- ncogene c-myc. Reptin52/TIP49b and Pontin52/TIP49a have antagonistic roles as Reptin/TIP49b represses gene activation mediated by beta-Catenin and c-myc, whereas Pontin52/TIP49a stimulates gene activation. Thus, Reptin52/TIP49b and Pontin52/TIP49a are transcriptional co-factors that work together to help control multiple pathways.
- 分子量
- 52 kDa
- 途径
- Telomere Maintenance
-
