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TOMM20 抗体 (AA 47-145)

TOMM20 适用: 人, 大鼠, 犬 WB, IF 宿主: 小鼠 Monoclonal 29-Tom20 unconjugated
产品编号 ABIN968798
发货至: 中国
  • 抗原 See all TOMM20 抗体
    TOMM20 (Mitochondrial Import Receptor Subunit TOM20 homolog (TOMM20))
    抗原表位
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 47-145
    适用
    • 37
    • 28
    • 27
    • 1
    • 1
    人, 大鼠, 犬
    宿主
    • 35
    • 2
    小鼠
    克隆类型
    • 24
    • 13
    单克隆
    标记
    • 21
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This TOMM20 antibody is un-conjugated
    应用范围
    • 19
    • 10
    • 9
    • 9
    • 9
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    交叉反应
    犬, 大鼠
    产品特性
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Human Tom20 aa. 47-145
    克隆位点
    29-Tom20
    亚型
    IgG1
    Top Product
    Discover our top product TOMM20 Primary Antibody
  • 说明

    Related Products: ABIN968537, ABIN967389

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    250 μg/mL
    缓冲液
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store undiluted at -20° C.
  • Krimmer, Rapaport, Ryan, Meisinger, Kassenbrock, Blachly-Dyson, Forte, Douglas, Neupert, Nargang, Pfanner: "Biogenesis of porin of the outer mitochondrial membrane involves an import pathway via receptors and the general import pore of the TOM complex." in: The Journal of cell biology, Vol. 152, Issue 2, pp. 289-300, (2001) (PubMed).

    Abe, Shodai, Muto, Mihara, Torii, Nishikawa, Endo, Kohda: "Structural basis of presequence recognition by the mitochondrial protein import receptor Tom20." in: Cell, Vol. 100, Issue 5, pp. 551-60, (2000) (PubMed).

    Hernández, Giner, Hernández-Yago: "Gene structure of the human mitochondrial outer membrane receptor Tom20 and evolutionary study of its family of processed pseudogenes." in: Gene, Vol. 239, Issue 2, pp. 283-91, (1999) (PubMed).

  • 抗原
    TOMM20 (Mitochondrial Import Receptor Subunit TOM20 homolog (TOMM20))
    别名
    Tom20 (TOMM20 产品)
    别名
    MAS20 antibody, MOM19 antibody, TOM20 antibody, 1810060K07Rik antibody, BB284719 antibody, Gm19268 antibody, mKIAA0016 antibody, tomm20 antibody, wu:fk47b11 antibody, zgc:73165 antibody, mas20 antibody, mom19 antibody, tom20 antibody, zgc:92628 antibody, translocase of outer mitochondrial membrane 20 antibody, translocase of outer mitochondrial membrane 20 homolog (yeast) antibody, Mitochondrial import receptor subunit TOM20 homolog antibody, translocase of outer mitochondrial membrane 20 homolog L homeolog antibody, translocase of outer mitochondrial membrane 20b antibody, TOMM20 antibody, Tomm20 antibody, tomm20a antibody, tomm-20 antibody, tomm20.L antibody, tomm20b antibody
    背景
    Many mitochondrial proteins are encoded by nuclear genes and synthesized in the cytosol as pre-proteins. These pre-proteins are targeted to the mitochondria where they are translocated across the outer and inner membranes of the mitochondria. At the outer membrane of the mitochondria, this process requires a multiprotein complex called the Translocase of the Outer Membrane of the mitochondria (TOM). The TOM complex includes receptor components, Tom20, 22, 37, and 70, as well as a multisubunit general import pore complex of 400 kDa. Tom20 contains a hydrophobic N-terminal region that anchors it to the outer membrane of the mitochondria, and a cytosolic region that contains a domain that facilitates binding to the basic amphiphilic targeting sequences of pre-proteins and a tetratricopeptide repeat (TPR) motif involved in interactions with Tom70. In yeast, Tom20 and Tom22 mediate the import of all pre-proteins known to use the general import machinery of the mitochondria. Thus, Tom20 is an important receptor for many mitochondrial pre-proteins that use the outer mitochondrial translocation complex.
    分子量
    18 kDa
    途径
    Unfolded Protein Response
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