ARHGAP4 抗体 (AA 843-955)
(3 references)Quick Overview for ARHGAP4 抗体 (AA 843-955) (ABIN968790)
抗原
See all ARHGAP4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 843-955
-
交叉反应
- 小鼠
-
产品特性
-
1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
-
免疫原
- Rat p115 aa. 843-955
-
亚型
- IgG1
-
-
anti-rho GTPase Activating Protein 4 (ARHGAP4) (N-Term) antibody
ARHGAP4 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-rho GTPase Activating Protein 4 (ARHGAP4) antibodyARHGAP4 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-rho GTPase Activating Protein 4 (ARHGAP4) (AA 1-986) antibodyARHGAP4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-rho GTPase Activating Protein 4 (ARHGAP4) (AA 881-986) antibodyARHGAP4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F7 unconjugated
anti-rho GTPase Activating Protein 4 (ARHGAP4) (C-Term) antibodyARHGAP4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-rho GTPase Activating Protein 4 (ARHGAP4) (C-Term) antibodyARHGAP4 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-rho GTPase Activating Protein 4 (ARHGAP4) antibodyARHGAP4 适用: 人, 小鼠, 大鼠 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
-
-
说明
-
Related Products: ABIN968545, ABIN967389
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 250 μg/mL
-
缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store undiluted at -20° C.
-
-
-
: "Biogenesis of N-cadherin-dependent cell-cell contacts in living fibroblasts is a microtubule-dependent kinesin-driven mechanism." in: Molecular biology of the cell, Vol. 13, Issue 1, pp. 285-301, (2002) (PubMed).
: "Transcytosis-associated protein (TAP)/p115 is a general fusion factor required for binding of vesicles to acceptor membranes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 2, pp. 527-31, (1995) (PubMed).
: "A novel 115-kD peripheral membrane protein is required for intercisternal transport in the Golgi stack." in: The Journal of cell biology, Vol. 118, Issue 5, pp. 1015-26, (1992) (PubMed).
-
: "Biogenesis of N-cadherin-dependent cell-cell contacts in living fibroblasts is a microtubule-dependent kinesin-driven mechanism." in: Molecular biology of the cell, Vol. 13, Issue 1, pp. 285-301, (2002) (PubMed).
-
- ARHGAP4 (rho GTPase Activating Protein 4 (ARHGAP4))
-
别名
- p115
-
背景
- Maturation and post translational modification of proteins occurs after their biosynthesis at the endoplasmic reticulum and their transport through the Golgi apparatus. The process involves the transport of vesicles carrying the proteins through a vectorial process of vesicle budding and fusion from the cis-compartment to the medial-compartment and the trans-compartment of the Golgi apparatus. p115 is a 959 amino acid protein located at the Golgi apparatus that, with the NEM-sensitive fusion protein and the soluble NSF attachment protein (SNAP), is required for vesicle transport from the cis-compartment to the medial-compartment. p115 protein is related to the yeast Uso1p essential for the vesicular transport from the endoplasmic reticulum to the Golgi. Native p115 appears to be a homo-oligomer, with two globular heads and a tail that resemble the overall structure of myosin. p115 is extracted from the Golgi apparatus with high salt or high pH, indicative of a membrane associated protein. p115 interacts with the golgi matrix protein GM130 but this interaction is disrupted by the Golgi fragmentation during mitosis and the phosphorylation of GM130. This antibody is routinely tested by western blot analysis.
-
分子量
- 115 kDa
-
途径
- Neurotrophin Signaling Pathway, Regulation of Cell Size
抗原
-
