Calreticulin 抗体 (AA 270-390)
(4 references)-
- 抗原 See all Calreticulin (CALR) 抗体
- Calreticulin (CALR)
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抗原表位
- AA 270-390
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适用
- 人, 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Calreticulin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 交叉反应
- 人, 大鼠
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Mouse Calreticulin aa. 270-390
- 克隆位点
- 16-Calreticulin
- 亚型
- IgG1
- Top Product
- Discover our top product CALR Primary Antibody
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anti-Calreticulin (CALR) (AA 196-310) antibody
CALR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calreticulin (CALR) (AA 18-193) antibodyCALR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calreticulin (CALR) antibodyCALR 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calreticulin (CALR) antibodyKO Validated CALR 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Calreticulin (CALR) (AA 18-417) antibodyCALR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 7B3D7 unconjugated
anti-Calreticulin (CALR) antibodyCALR 适用: 人, 小鼠 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 1G6A7 unconjugated
anti-Calreticulin (CALR) (N-Term) antibodyCALR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calreticulin (CALR) (AA 1-417) antibodyCALR 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G11-1A9 unconjugated
anti-Calreticulin (CALR) antibodyCALR 适用: 人, 小鼠 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1G6A7 unconjugated
anti-Calreticulin (CALR) antibodyCALR 适用: 人 WB, IHC, IP, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
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- 说明
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Related Products: ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20° C.
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: "Calreticulin is directly involved in anti-alpha3 integrin antibody-mediated secretion and activation of matrix metalloprotease-2." in: Biochemical and biophysical research communications, Vol. 283, Issue 2, pp. 297-302, (2001) (PubMed).
: "Calreticulin functions in vitro as a molecular chaperone for both glycosylated and non-glycosylated proteins." in: The EMBO journal, Vol. 18, Issue 23, pp. 6718-29, (2000) (PubMed).
: "Calreticulin displays in vivo peptide-binding activity and can elicit CTL responses against bound peptides." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 11, pp. 6426-32, (1999) (PubMed).
: "Determination of the sequence of an expressible cDNA clone encoding ERp60/calregulin by the use of a novel nested set method." in: Gene, Vol. 120, Issue 2, pp. 217-25, (1992) (PubMed).
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: "Calreticulin is directly involved in anti-alpha3 integrin antibody-mediated secretion and activation of matrix metalloprotease-2." in: Biochemical and biophysical research communications, Vol. 283, Issue 2, pp. 297-302, (2001) (PubMed).
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- 抗原
- Calreticulin (CALR)
- 别名
- Calreticulin (CALR 产品)
- 别名
- CRT antibody, RO antibody, SSA antibody, cC1qR antibody, crc antibody, crt antibody, Calregulin antibody, CG9429 antibody, Clr antibody, Dmel\\CG9429 antibody, anon-EST:Liang-2.11 antibody, anon-EST:Liang-2.17 antibody, anon-EST:fe3D7 antibody, clone 2.11 antibody, clone 2.17 antibody, eth antibody, potp antibody, cc1qr antibody, ssa antibody, NV19007 antibody, CRP55 antibody, ERp60 antibody, HACBP antibody, CHOT1 antibody, CHT1 antibody, CT1 antibody, AA589632 antibody, CRTR antibody, Creat antibody, CCDS1 antibody, calrl2 antibody, fc66d10 antibody, wu:fc66d10 antibody, wu:fj50c03 antibody, zgc:66153 antibody, calreticulin antibody, calreticulin L homeolog antibody, Calreticulin antibody, putative calreticulin antibody, solute carrier family 6 member 8 antibody, solute carrier family 6 (neurotransmitter transporter, creatine), member 8 antibody, CALR antibody, calr.L antibody, Crt antibody, crt antibody, CRT antibody, Calr antibody, calr antibody, LMJF_31_2600 antibody, Crc antibody, Slc6a8 antibody, SLC6A8 antibody, LOC8269812 antibody
- 背景
- Proteins undergo numerous modifications, including folding, translocation, and degradation. During such modifications, polypeptides are rarely in a native, stable state. Molecular chaperones are a diverse group of proteins that modulate polypeptide stability through ATP-dependent folding. Many chaperone proteins are found in the endoplasmic reticulum (ER). Calreticulin is a luminal ER protein that is 39% homologous to the ER chaperone protein, calnexin. Calreticulin contains a C-terminal KDEL ER retention signal, and can bind Ca2+, Zn2+, ATP, and the proteins, ERp57 and protein disulfide isomerase. The molecular chaperone activities of calreticulin may include folding of both Asn-linked glycoproteins and non-glycosylated proteins. In addition, calreticulin is a component of MHC I/transporter associated with Ag presentation (TAP) complex where it may function in peptide assembly onto nascent class I molecules. Calreticulin may also function in integrin signaling, since it binds a3-integrin subunits and regulates integrin-mediated metalloprotease secretion. Thus, calreticulin may be involved in Ca2+ storage, cell adhesion, and protein folding. This antibody is routinely tested by western blot analysis.
- 分子量
- 60 kDa
- 途径
- Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response
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