Coilin 抗体 (AA 226-332)
(2 references)Quick Overview for Coilin 抗体 (AA 226-332) (ABIN968730)
抗原
See all Coilin (COIL) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 226-332
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交叉反应
- 小鼠, 大鼠
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产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Human Coilin aa. 226-332
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亚型
- IgG1
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anti-Coilin (COIL) (AA 319-538) antibody
COIL 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coilin (COIL) (AA 297-576) antibodyCOIL 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Coilin (COIL) (AA 1-576) antibodyCOIL 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Coilin (COIL) (AA 477-575) antibodyCOIL 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4B8 unconjugated
anti-Coilin (COIL) (AA 1-576) antibodyCOIL 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Coilin (COIL) (AA 297-576) antibodyCOIL 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Coilin (COIL) (AA 73-86) antibodyVerified COIL 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Coilin (COIL) (AA 460-509) antibodyCOIL 适用: 人, 斑马鱼, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Coilin (COIL) (C-Term) antibodyCOIL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Coilin (COIL) antibodyCOIL 适用: 人 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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说明
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Related Products: ABIN968586, ABIN967389
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 250 μg/mL
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缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store undiluted at -20°C.
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: "Coilin shuttles between the nucleus and cytoplasm in Xenopus oocytes." in: Molecular biology of the cell, Vol. 10, Issue 10, pp. 3425-34, (1999) (PubMed).
: "Human autoantibody to a novel protein of the nuclear coiled body: immunological characterization and cDNA cloning of p80-coilin." in: The Journal of experimental medicine, Vol. 173, Issue 6, pp. 1407-19, (1991) (PubMed).
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: "Coilin shuttles between the nucleus and cytoplasm in Xenopus oocytes." in: Molecular biology of the cell, Vol. 10, Issue 10, pp. 3425-34, (1999) (PubMed).
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- Coilin (COIL)
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别名
- Coilin
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背景
- Ramon Cajal described small silver-staining organelles in the nuclei of pyramidal neurons, which have been referred to as cajal bodies or coiled bodies. An 80 kDa protein called p80 coilin was identified through its co-localization to coiled bodies. Coilin is a molecular marker of coiled bodies, but can also be found in the nucleoplasm, and may shuttle back and forth between the cytoplasm and nucleoplasm. Studies of GFP-coilin show that coiled bodies can move within the nucleoplasm to and from nucleoli. Other proteins that have been co-localized with coilin to the coiled bodies include cell cycle proteins, snRNPs, U3 snRNA, U7 snRNA, and several nucleolar proteins. Coiled bodies may recruit U7 snRNP and the stem-loop-binding protein to the chromosomal sites of histone gene transcription. Possibly, coilin is important for the formation of coiled bodies that act as sites for preassembly of transcriptosomes, which facilitate gene transcription and RNA processing.
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分子量
- 80 kDa
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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