Dynamin 1-Like 抗体 (AA 19-201)
(1 reference)Quick Overview for Dynamin 1-Like 抗体 (AA 19-201) (ABIN968652)
抗原
See all Dynamin 1-Like (DNM1L) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 19-201
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交叉反应
- 小鼠, 大鼠, 犬
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产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Human Drp1 aa. 19-201
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亚型
- IgG2a
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anti-Dynamin 1-Like (DNM1L) (AA 69-213) antibody
DNM1L 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 4A4C7 unconjugated
anti-Dynamin 1-Like (DNM1L) (AA 69-213) antibodyDNM1L 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 4E11B11 unconjugated
anti-Dynamin 1-Like (DNM1L) (AA 1-710) antibodyDNM1L 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3B5 unconjugated
anti-Dynamin 1-Like (DNM1L) antibodyDNM1L 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2E7 unconjugated
anti-Dynamin 1-Like (DNM1L) antibodyDNM1L 适用: 人, 小鼠, 大鼠, 猴, 犬 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4F6 unconjugated
anti-Dynamin 1-Like (DNM1L) antibodyDNM1L 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 3F3 unconjugated
anti-Dynamin 1-Like (DNM1L) (AA 411-710) antibodyDNM1L 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dynamin 1-Like (DNM1L) (AA 496-710) antibodyDNM1L 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dynamin 1-Like (DNM1L) (C-Term) antibodyDNM1L 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dynamin 1-Like (DNM1L) (pSer637) antibodyDNM1L 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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说明
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Related Products: ABIN968551, ABIN967389
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 250 μg/mL
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缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store undiluted at -20° C.
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: "drp, a novel protein expressed at high cell density but not during growth arrest." in: DNA and cell biology, Vol. 17, Issue 5, pp. 437-47, (1998) (PubMed).
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: "drp, a novel protein expressed at high cell density but not during growth arrest." in: DNA and cell biology, Vol. 17, Issue 5, pp. 437-47, (1998) (PubMed).
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- Dynamin 1-Like (DNM1L)
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别名
- Drp1
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背景
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In culture, cell density can have profound effects on gene expression, enzymatic activity, and cell signaling pathways. Using differential screening of cDNAs from low-passage nontumorigenic teratocarcinoma cells versus high passage tumorigenic cells, a protein was identified that is regulated in cell-density dependent manner. This protein, density-regulated protein 1 (drp1), contains putative sites for N-myristoylation and phosphorylation sites for cAMP and/or cGMP-dependent kinase, casein kinase II, and PKC. The expression of drp1 is enriched in high density cultures of both nontumorigenic and tumorigenic cell lines and is widely detected in adult organs, especially skeletal and cardiac muscle. In addition, increased expression of drp1 is not due to growth arrest as a result of serum starvation or TGF-beta treatment nor is it a result of factors found in the media of high density cultures. Interestingly, drp1 is expressed highest in skeletal and cardiac muscle where unique cell-cell contacts are involved in muscle cell membrane depolarization and contraction. Thus, drp1 expression may be regulated by signaling pathways related to specific types of cell-cell contacts. This antibody is routinely tested by western blot analysis.
Synonyms: Density Regulated Protein-1 -
分子量
- 27 kDa
抗原
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