Dynamin Associated Protein 160 (DAP160) (AA 800-909) 抗体
Cited in 2+ publications.
The 小鼠 单克隆 anti-Dynamin Associated Protein 160 antibody (Clone 29-Intersectin) (ABIN968598) specifically detects Dynamin Associated Protein 160 in IF 和 WB.
The antibody is reactive with 小鸡, 小鼠 和 大鼠 samples.
(2 references)
产品编号 ABIN968598
发货至:
中国
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Quick Overview for Dynamin Associated Protein 160 (DAP160) (AA 800-909) 抗体 (ABIN968598)
抗原
Dynamin Associated Protein 160 (DAP160)
适用
小鸡, 小鼠, 大鼠
宿主
小鼠
克隆类型
单克隆
应用范围
Immunofluorescence (IF), Western Blotting (WB)
克隆位点
29-Intersectin
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抗原表位
- AA 800-909
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交叉反应
- 大鼠, 小鸡
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产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Mouse Ese-1 aa. 800-909
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亚型
- IgG1
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说明
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Related Products: ABIN968545, ABIN967389
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 250 μg/mL
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缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store undiluted at -20°C.
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: "EHSH1/intersectin, a protein that contains EH and SH3 domains and binds to dynamin and SNAP-25. A protein connection between exocytosis and endocytosis?" in: The Journal of biological chemistry, Vol. 274, Issue 26, pp. 18446-54, (1999) (PubMed).
: "The EH and SH3 domain Ese proteins regulate endocytosis by linking to dynamin and Eps15." in: The EMBO journal, Vol. 18, Issue 5, pp. 1159-71, (1999) (PubMed).
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: "EHSH1/intersectin, a protein that contains EH and SH3 domains and binds to dynamin and SNAP-25. A protein connection between exocytosis and endocytosis?" in: The Journal of biological chemistry, Vol. 274, Issue 26, pp. 18446-54, (1999) (PubMed).
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- Dynamin Associated Protein 160 (DAP160)
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别名
- Intersectin
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背景
- ESE-1 (epithelium-specific, EH domain and SH3 domain regulator of endocytosis) contains two N-terminal EH (Ep15 homology) domains, a central coiled-coil domain, and five C-terminal SH3 domains. ESE-1 is also known as the adaptor protein Intersectin. Intersectin constitutively associates with Eps15 to form a complex that is analogous to the yeast Pan1p-End3p complex, which is required for endocytosis and organization of the actin cytoskeleton. The EH, coiled-coil, and SH3 domains of intersectin bind epsin family proteins, SNAP25 and SNAP23, and dynamin, respectively. Thus, intersectin functions in complex with Eps15 to regulate endocytosis by linking components of the endocytic machinery.
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分子量
- 140/200 kDa
抗原
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