STX8 抗体 (AA 57-164)
(2 references)Quick Overview for STX8 抗体 (AA 57-164) (ABIN968489)
抗原
See all STX8 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 57-164
-
交叉反应
- 人, 犬, 大鼠
-
产品特性
-
1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
-
免疫原
- Mouse Syntaxin 8 aa. 57-164
-
亚型
- IgG2a
-
-
anti-Syntaxin 8 (STX8) antibody
STX8 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 8 (STX8) (AA 1-236) antibodySTX8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H1-1D11 unconjugated
anti-Syntaxin 8 (STX8) antibodySTX8 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 8 (STX8) (AA 1-236) antibodySTX8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 8 (STX8) (AA 1-236) antibodySTX8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Syntaxin 8 (STX8) (AA 1-215), (Cytoplasmic Domain) antibodySTX8 适用: 人, 小鼠, 大鼠, Hamster WB, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 8 (STX8) (AA 1-215) antibodySTX8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 8 (STX8) (AA 161-210) antibodySTX8 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 8 (STX8) (AA 162-211) antibodySTX8 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 斑马鱼, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 8 (STX8) (AA 1-215) antibodySTX8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
说明
-
Related Products: ABIN967389, ABIN968536
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 250 μg/mL
-
缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store undiluted at -20°C.
-
-
-
: "Three novel proteins of the syntaxin/SNAP-25 family." in: The Journal of biological chemistry, Vol. 273, Issue 51, pp. 34171-9, (1999) (PubMed).
: "Molecular cloning, expression analysis, and chromosomal localization of human syntaxin 8 (STX8)." in: Biochemical and biophysical research communications, Vol. 257, Issue 2, pp. 577-83, (1999) (PubMed).
-
: "Three novel proteins of the syntaxin/SNAP-25 family." in: The Journal of biological chemistry, Vol. 273, Issue 51, pp. 34171-9, (1999) (PubMed).
-
- STX8 (Syntaxin 8 (STX8))
-
别名
- Syntaxin 8
-
背景
- Eukaryotic protein trafficking involves the packaging of molecules into membranous vesicles that bud from a donor compartment, travel to a specific destination, fuse, and release their components into an acceptor compartment. Recognition between vesicle and acceptor membrane is mediated by the pairing of the integral membrane SNARE proteins. The stable interaction between vesicle proteins (v-SNAREs) and target proteins (t-SNAREs) juxtaposes the membranes and results in an activated docking state and/or membrane fusion. The syntaxin protein family contains a number of members that serve as functional t-SNAREs. One member of this family, syntaxin 8, has two coiled-coil domains, one in the N-terminus and one toward the C-terminus. The C-terminal domain is homologous to a similar domain in syntaxin 6 and is predicted to interact in the formation of SNARE complexes, while a hydrophobic domain in the C-terminus may be involved in membrane anchoring. Syntaxin-8 is ubiquitously expressed, but is present at high levels in the heart and localizes specifically to the ER. Thus, syntaxin-8 is a t-SNARE that is thought to be involved in the early secretory pathway of many different cell types.
-
分子量
- 27 kDa
-
途径
- Synaptic Vesicle Exocytosis
抗原
-
