NMT2 抗体 (AA 10-119)
(1 reference)Quick Overview for NMT2 抗体 (AA 10-119) (ABIN968466)
抗原
See all NMT2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 10-119
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产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Human NMT-2 aa. 10-119
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亚型
- IgG1
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anti-N-Myristoyltransferase 2 (NMT2) (AA 1-120) antibody
NMT2 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-N-Myristoyltransferase 2 (NMT2) antibodyNMT2 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2A5 unconjugated
anti-N-Myristoyltransferase 2 (NMT2) (AA 1-498) antibodyNMT2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E12-4B5 unconjugated
anti-N-Myristoyltransferase 2 (NMT2) (AA 1-120) antibodyNMT2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-N-Myristoyltransferase 2 (NMT2) (AA 16-46), (N-Term) antibodyNMT2 适用: 人 WB 宿主: 兔 Polyclonal RB4641-4642 unconjugated
anti-N-Myristoyltransferase 2 (NMT2) (AA 1-498) antibodyNMT2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-N-Myristoyltransferase 2 (NMT2) (AA 125-153), (C-Term) antibodyNMT2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 250 μg/mL
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缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store undiluted at -20°C.
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: "A second mammalian N-myristoyltransferase." in: The Journal of biological chemistry, Vol. 273, Issue 12, pp. 6595-8, (1998) (PubMed).
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: "A second mammalian N-myristoyltransferase." in: The Journal of biological chemistry, Vol. 273, Issue 12, pp. 6595-8, (1998) (PubMed).
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- NMT2 (N-Myristoyltransferase 2 (NMT2))
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别名
- NMT-2
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背景
- Myristoylation is an essential cotranslational modification for many mammalian, viral, and fungal signaling proteins. N-terminal myristoylation is a lipid modification that is catalyzed by N-myristoyltransferase (NMT). NMT transfers myristic acid from myristoyl coenzyme A to the amino group of a protein's N-terminal glycine residue. This modification is important for localization and/or function of many of these proteins. Two human NMTs (NMT-1, NMT-2) have been identified. These proteins share 95% amino acid identity with their mouse homologs. NMT-1 is processed to form four protein isoforms with molecular weights ranging from 49-68 kDa. It is not known if these four isoforms are derived from single or multiple gene(s) and their exact functional roles are yet to be determined. In contrast to NMT-1, NMT-2 is a single 65 kDa protein. It contains 77% sequence identity with NMT-1, indicating that these proteins comprise two distinct families with overlapping, but distinct, substrate preferences. Additionally, NMT enzymatic activity is increased in colorectal tumors. Thus, NMTs are transferases whose function is essential for biological function of a variety of signaling proteins.
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分子量
- 65 kDa
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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