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HDAC3 抗体 (AA 309-425)

HDAC3 适用: 人, 小鼠, 大鼠, 犬 WB, IF 宿主: 小鼠 Monoclonal 40-HDAC3 unconjugated
产品编号 ABIN968378
发货至: 中国
  • 抗原 See all HDAC3 抗体
    HDAC3 (Histone Deacetylase 3 (HDAC3))
    抗原表位
    • 22
    • 20
    • 16
    • 10
    • 8
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 309-425
    适用
    • 114
    • 66
    • 63
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬
    宿主
    • 87
    • 26
    • 1
    小鼠
    克隆类型
    • 89
    • 25
    单克隆
    标记
    • 65
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This HDAC3 antibody is un-conjugated
    应用范围
    • 99
    • 53
    • 39
    • 27
    • 27
    • 26
    • 16
    • 15
    • 14
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    交叉反应
    小鼠, 大鼠, 犬
    产品特性
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Human HDAC3 aa. 309-425
    克隆位点
    40-HDAC3
    亚型
    IgG1
    Top Product
    Discover our top product HDAC3 Primary Antibody
  • 说明

    Related Products: ABIN968536, ABIN967389

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    250 μg/mL
    缓冲液
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store undiluted at -20° C.
  • 抗原
    HDAC3 (Histone Deacetylase 3 (HDAC3))
    别名
    HDAC3 (HDAC3 产品)
    别名
    CG2128 antibody, DHDAC3 antibody, DmHDAC3 antibody, Dmel\\CG2128 antibody, Dromel_CG2128_FBtr0078767_hdac3_mORF antibody, HDAC antibody, HDAC3 antibody, Hdac 3 antibody, dHDAC3 antibody, dmHDA402 antibody, hdac3 antibody, HDm antibody, hd3 antibody, RPD3 antibody, XRpd3 antibody, rpd3-2 antibody, HD3 antibody, RPD3-2 antibody, AW537363 antibody, zgc:55927 antibody, Histone deacetylase 3 antibody, histone deacetylase 3 antibody, histone deacetylase 3 S homeolog antibody, HDAC3 antibody, hdac3 antibody, CNL05260 antibody, Hdac3 antibody, hdac3.S antibody
    背景
    Regulation of gene expression occurs at multiple levels and is mediated by numerous factors. DNA-binding proteins such as histones function to spatially organize the DNA into chromatin. The spatial organization of chromatin is also important for gene expression, and modifications to DNA-binding proteins have profound effects on gene expression. Human Histone Deacetylase 3 (HDAC3) is a protein of approximately 50 kDa that removes acetyl groups from the epsilon-amino groups of lysines in histones, thus in competition with the acetylases. HDAC3 is the third member of this family of deacetylases, related to the yeast RPD3 gene, which affect transcription of certain human genes. HDAC3 importance is reflected in its distribution in virtually every cell type examined. In in vitro assays, HDAC3 exhibited activity towards histones H3 and H4 acetylated in vivo. Furthermore, inhibitors of deacetylation, such as sodium butyrate, inhibited HDAC3 activity. Further studies will determine the specific role of HDAC3 in regulating gene expression.
    Synonyms: Histone Deacetylase-3
    分子量
    50 kDa
    途径
    Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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