HDAC3 抗体 (AA 309-425)
Quick Overview for HDAC3 抗体 (AA 309-425) (ABIN968378)
抗原
See all HDAC3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 309-425
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交叉反应
- 小鼠, 大鼠, 犬
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产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Human HDAC3 aa. 309-425
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亚型
- IgG1
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anti-Histone Deacetylase 3 (HDAC3) (AA 299-428) antibody
HDAC3 适用: 人 WB, IHC, IF, IP, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 3 (HDAC3) (C-Term) antibodyHDAC3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 3 (HDAC3) (pSer424) antibodyHDAC3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 3 (HDAC3) (AA 1-428) antibodyHDAC3 适用: 人 WB, ELISA, IHC, IF, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 3 (HDAC3) (AA 319-428) antibodyHDAC3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2A3 unconjugated
anti-Histone Deacetylase 3 (HDAC3) antibodyHDAC3 适用: 人, 小鼠, 大鼠, 犬, 小鸡 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 3 (HDAC3) (C-Term) antibodyHDAC3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 3 (HDAC3) (AA 1-428) antibodyHDAC3 适用: 人 ELISA, IF, IP 宿主: 小鼠 Monoclonal 2F9-4B7 unconjugated
anti-Histone Deacetylase 3 (HDAC3) (AA 31-130) antibodyHDAC3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 3 (HDAC3) antibodyHDAC3 适用: 人 WB, ELISA, IHC 宿主: 兔 Monoclonal 4D4 unconjugated Recombinant Antibody
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说明
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Related Products: ABIN968536, ABIN967389
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 250 μg/mL
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缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store undiluted at -20° C.
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- HDAC3 (Histone Deacetylase 3 (HDAC3))
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别名
- HDAC3
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背景
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Regulation of gene expression occurs at multiple levels and is mediated by numerous factors. DNA-binding proteins such as histones function to spatially organize the DNA into chromatin. The spatial organization of chromatin is also important for gene expression, and modifications to DNA-binding proteins have profound effects on gene expression. Human Histone Deacetylase 3 (HDAC3) is a protein of approximately 50 kDa that removes acetyl groups from the epsilon-amino groups of lysines in histones, thus in competition with the acetylases. HDAC3 is the third member of this family of deacetylases, related to the yeast RPD3 gene, which affect transcription of certain human genes. HDAC3 importance is reflected in its distribution in virtually every cell type examined. In in vitro assays, HDAC3 exhibited activity towards histones H3 and H4 acetylated in vivo. Furthermore, inhibitors of deacetylation, such as sodium butyrate, inhibited HDAC3 activity. Further studies will determine the specific role of HDAC3 in regulating gene expression.
Synonyms: Histone Deacetylase-3 -
分子量
- 50 kDa
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途径
- Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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