电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CSRP2 抗体 (AA 601-722)

This anti-CSRP2 antibody is a 小鼠 单克隆 antibody detecting CSRP2 in WB 和 IF. Suitable for 人, 小鼠, 大鼠 和 犬. This Primary Antibody has been cited in 6+ publications.
产品编号 ABIN968371
发货至: 中国

Quick Overview for CSRP2 抗体 (AA 601-722) (ABIN968371)

抗原

See all CSRP2 抗体
CSRP2 (Cysteine and Glycine-Rich Protein 2 (CSRP2))

适用

  • 47
  • 22
  • 21
  • 17
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
人, 小鼠, 大鼠, 犬

宿主

  • 58
  • 3
  • 1
小鼠

克隆类型

  • 62
单克隆

标记

  • 19
  • 5
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CSRP2 antibody is un-conjugated

应用范围

  • 37
  • 26
  • 26
  • 22
  • 11
  • 7
  • 6
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF)

克隆位点

8-DLP1
  • 抗原表位

    • 15
    • 15
    • 7
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 601-722

    交叉反应

    小鼠, 人, 犬

    产品特性

    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Please refer to us for technical protocols.

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    免疫原

    Rat DLP1 aa. 601-722

    亚型

    IgG1
  • 说明

    Related Products: ABIN967389, ABIN968545

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    250 μg/mL

    缓冲液

    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store undiluted at -20°C.
  • Bossy, Petrilli, Klinglmayr, Chen, Lütz-Meindl, Knott, Masliah, Schwarzenbacher, Bossy-Wetzel: "S-Nitrosylation of DRP1 does not affect enzymatic activity and is not specific to Alzheimer's disease." in: Journal of Alzheimer's disease : JAD, Vol. 20 Suppl 2, Issue 6, pp. S513-26, (2010) (PubMed).

    Estaquier, Arnoult: "Inhibiting Drp1-mediated mitochondrial fission selectively prevents the release of cytochrome c during apoptosis." in: Cell death and differentiation, Vol. 14, Issue 6, pp. 1086-94, (2007) (PubMed).

    Karbowski, Neutzner, Youle: "The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division." in: The Journal of cell biology, Vol. 178, Issue 1, pp. 71-84, (2007) (PubMed).

    Duvezin-Caubet, Jagasia, Wagener, Hofmann, Trifunovic, Hansson, Chomyn, Bauer, Attardi, Larsson, Neupert, Reichert: "Proteolytic processing of OPA1 links mitochondrial dysfunction to alterations in mitochondrial morphology." in: The Journal of biological chemistry, Vol. 281, Issue 49, pp. 37972-9, (2006) (PubMed).

    Jofuku, Ishihara, Mihara: "Analysis of functional domains of rat mitochondrial Fis1, the mitochondrial fission-stimulating protein." in: Biochemical and biophysical research communications, Vol. 333, Issue 2, pp. 650-9, (2005) (PubMed).

    Yoon, Pitts, Dahan, McNiven: "A novel dynamin-like protein associates with cytoplasmic vesicles and tubules of the endoplasmic reticulum in mammalian cells." in: The Journal of cell biology, Vol. 140, Issue 4, pp. 779-93, (1998) (PubMed).

  • 抗原

    CSRP2 (Cysteine and Glycine-Rich Protein 2 (CSRP2))

    别名

    DLP1

    背景

    Dynamins, phosphoproteins with intrinsic GTPase activities, play an important role during early endocytosis. The GTPase activity is stimulated in vitro by microtubules, SH3 domain containing-proteins, and Protein Kinase (PKC)- mediated phosphorylation. Although highly related, dynamins are differentially expressed in an organism. For instance, dynamin I is found only in the nervous system, dynamin II is ubiquitously expressed, and dynamin III is located in lung, testis and brain. Due to four alternative splicing products for each of the dynamins, the dynamin family contains at least 12 different members. The Dynamin Like Protein-1 (DLP1) is a new member of the dynamin family of proteins. DLP1 (also known as DVLP) is widely expressed as two alternatively spliced products, each with different tissue expression patterns. The larger product is about 84 kDa and reportedly found only in the brain, whereas the 79 kDa product is ubiquitously expressed. Unlike dynamins I-III which co-localize with endocytotic vesicles, DLP1 is found aligned with microtubules and with the endoplasmic reticulum, suggesting a secretory function for this novel protein.
    Synonyms: Dynamin Like Protein-1, DVLP

    分子量

    79-84 kDa
You are here:
Chat with us!