Thymopoietin 抗体 (AA 34-156)
(5 references)Quick Overview for Thymopoietin 抗体 (AA 34-156) (ABIN968307)
抗原
See all Thymopoietin (TMPO) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 34-156
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交叉反应
- 小鼠, 人, 犬
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产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Rat LAP2 aa. 34-156
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亚型
- IgG1
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anti-Thymopoietin (TMPO) (AA 1-410) antibody
TMPO 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thymopoietin (TMPO) (AA 1-50) antibodyTMPO 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Thymopoietin (TMPO) (AA 1-243) antibodyTMPO 适用: 人 WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Thymopoietin (TMPO) (AA 1-454) antibodyTMPO 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Thymopoietin (TMPO) antibodyTMPO 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Thymopoietin (TMPO) (N-Term) antibodyTMPO 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thymopoietin (TMPO) (AA 650-750) antibodyTMPO 适用: 人 WB, IF, IP, ICC 宿主: 小鼠 Monoclonal 3A3 unconjugated
anti-Thymopoietin (TMPO) (N-Term) antibodyTMPO 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马, Pig, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Thymopoietin (TMPO) (AA 143-192) antibodyTMPO 适用: 人, 小鼠, Cow, 犬, 豚鼠, 兔, 马, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Thymopoietin (TMPO) (N-Term) antibodyTMPO 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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说明
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Related Products: ABIN967389
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 250 μg/mL
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缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store undiluted at -20° C.
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: "Mouse germ cell-less as an essential component for nuclear integrity." in: Molecular and cellular biology, Vol. 23, Issue 4, pp. 1304-15, (2003) (PubMed).
: "Reorganization of the microtubule array in prophase/prometaphase requires cytoplasmic dynein-dependent microtubule transport." in: The Journal of cell biology, Vol. 158, Issue 6, pp. 997-1003, (2002) (PubMed).
: "Detergent-salt resistance of LAP2alpha in interphase nuclei and phosphorylation-dependent association with chromosomes early in nuclear assembly implies functions in nuclear structure dynamics." in: The EMBO journal, Vol. 17, Issue 16, pp. 4887-902, (1998) (PubMed).
: "The major nuclear envelope targeting domain of LAP2 coincides with its lamin binding region but is distinct from its chromatin interaction domain." in: The Journal of biological chemistry, Vol. 273, Issue 7, pp. 4213-9, (1998) (PubMed).
: "Cloning of a cDNA for lamina-associated polypeptide 2 (LAP2) and identification of regions that specify targeting to the nuclear envelope." in: The EMBO journal, Vol. 14, Issue 8, pp. 1626-36, (1995) (PubMed).
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: "Mouse germ cell-less as an essential component for nuclear integrity." in: Molecular and cellular biology, Vol. 23, Issue 4, pp. 1304-15, (2003) (PubMed).
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- Thymopoietin (TMPO)
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别名
- LAP2
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背景
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A specialized extension of the ER, the nuclear envelope (NE) forms the nuclear compartment boundary in eukaryotic cells. It contains numerous pore complexes and the nucleoplasmic side is linked to nuclear lamina. The nuclear lamina composes the structural framework for the NE and serves as a chromatin anchor site, thus, playing a major role in interphase nuclear organization. Many proteins are associated with lamina, particularly the LAPs (Lamina-Associated Polypeptides). LAP2 (also known as LAP2beta) is a hydrophilic protein with a single transmembrane segment near the C-terminus. Thus, it has been defined as a type II integral membrane protein with the majority of its structure exposed to the nucleoplasm. LAP2 binding to lamins contributes to the attachment of the nuclear lamina to the inner nuclear membrane. LAP2 also binds to chromatin, implying its role in chromosomal organization during mitosis. Mitotic phosphorylation of LAP2 regulates its binding to lamins and chromosomes during the disassembly and reassembly of mitosis. Thus, LAP2 is a nuclear protein that plays a role in the organization of the NE during cell cycle progression.
Synonyms: LAP2beta, Lamina-Associated Polypeptides -
分子量
- 53 kDa
抗原
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