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Fatty Acid Synthase 抗体 (AA 9-202)

Name: Fatty Acid Synthase 抗体 (AA 9-202)
SKU: ABIN968278
Availability: OutOfStock

This anti-Fatty Acid Synthase antibody is a 小鼠单克隆 antibody detecting Fatty Acid Synthase in WB 和 IF. Suitable for 人, 小鼠, 大鼠, 兔和犬. This Primary Antibody has been cited in 3+ publications.

Western blot analysis of Fatty Acid Synthase on HepG2 cell lysate. (Fatty Acid Synthase 抗体 (AA 9-202))

Immunofluorescent staining of MDCK cells with anti-FAS antibody. (Fatty Acid Synthase 抗体 (AA 9-202))

2 images

(3 references)

产品编号 ABIN968278

发货至: 中国

Quick Overview for Fatty Acid Synthase 抗体 (AA 9-202) (ABIN968278)

抗原

See all Fatty Acid Synthase (FASN) 抗体

Fatty Acid Synthase (FASN)

适用

人, 小鼠, 大鼠, 兔, 犬

宿主

小鼠

克隆类型

单克隆

标记

This Fatty Acid Synthase antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF)

克隆位点

23-Fatty Acid Synthase

Discover our top product FASN Primary Antibody

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AA 9-202

交叉反应

犬, 小鼠, 兔, 大鼠

产品特性

1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

纯化方法

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

免疫原

Human Fatty Acid Synthase aa. 9-202

亚型

IgG1
anti-Fatty Acid Synthase (FASN) (AA 1-439) antibody
FASN 适用: 人 WB, IP, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3F2-1F3 unconjugated

anti-Fatty Acid Synthase (FASN) (AA 2212-2511) antibody
FASN 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-Fatty Acid Synthase (FASN) (N-Term) antibody
KO Validated FASN 适用: 人 WB, IP, IF, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Fatty Acid Synthase (FASN) antibody
FASN 适用: 人 WB, IHC, IP, IF 宿主: 兔 Monoclonal unconjugated

anti-Fatty Acid Synthase (FASN) (AA 942-973) antibody
FASN 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 497CT15-2-5 unconjugated

anti-Fatty Acid Synthase (FASN) (AA 942-973) antibody
FASN 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB17743 unconjugated

anti-Fatty Acid Synthase (FASN) (AA 942-973) antibody
FASN 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-Fatty Acid Synthase (FASN) (AA 2243-2505) antibody
FASN 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Fatty Acid Synthase (FASN) (AA 1-226) antibody
FASN 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Fatty Acid Synthase (FASN) (AA 651-750) antibody
FASN 适用: 人, 小鼠, 大鼠, 山羊 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

说明

Related Products: ABIN968587, ABIN967389

限制

仅限研究用
状态

Liquid

浓度

250 μg/mL

缓冲液

Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store undiluted at -20° C.
Chirala, Huang, Jayakumar, Sakai, Wakil: "Animal fatty acid synthase: functional mapping and cloning and expression of the domain I constituent activities." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 11, pp. 5588-93, (1997) (PubMed).

Jayakumar, Tai, Huang, al-Feel, Hsu, Abu-Elheiga, Chirala, Wakil: "Human fatty acid synthase: properties and molecular cloning." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 19, pp. 8695-9, (1995) (PubMed).

Smith: "The animal fatty acid synthase: one gene, one polypeptide, seven enzymes." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 8, Issue 15, pp. 1248-59, (1995) (PubMed).
抗原

Fatty Acid Synthase (FASN)

别名

Fatty Acid Synthase

背景

Fatty acid biosynthesis occurs in all living organisms and provides essential components of biological membranes as well as a form of energy storage. Animal fatty acid synthase (FAS) is a multifunctional enzyme that catalyzes the synthesis of long-chain fatty acids via sequential condensation of two-carbon units from malonyl-CoA, an intermediate derived from the carboxylation of Acetyl-CoA. FAS is a homodimer of a multifunctional subunit protein that contains seven distinct activities and a site for the prosthetic group 4'-phosphopantetheine (acyl carrier protein). These domains are oriented from N-terminus to C-terminus as follows: beta-keto-acyl synthase, acetyl and malonyl transacylases, enoyl reductase, ketoacyl reductase, acyl carrier protein, and thioesterase. Although all domains are found on each subunit, they are only active following the homodimerization of subunits in an antiparallel (head-to-tail) orientation. This juxtaposition and cooperation between domains forms two centers for acyl chain assembly. Alternative substrates and chain-terminating mechanisms allow for the production of a variety of fatty acids with different lengths and structures.

分子量

265 kDa

途径

AMPK Signaling