GTF2I 抗体 (AA 17-123)
(1 reference)Quick Overview for GTF2I 抗体 (AA 17-123) (ABIN968264)
抗原
See all GTF2I 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 17-123
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交叉反应
- 犬, 小鼠, 大鼠
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产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Human BAP-135 aa. 17-123
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亚型
- IgG1
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anti-General Transcription Factor III (GTF2I) (AA 36-274) antibody
GTF2I 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3E2 unconjugated
anti-General Transcription Factor III (GTF2I) (AA 1-976) antibodyGTF2I 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-General Transcription Factor III (GTF2I) (AA 956-985), (C-Term) antibodyGTF2I 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB20983 unconjugated
anti-General Transcription Factor III (GTF2I) (N-Term) antibodyGTF2I 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-General Transcription Factor III (GTF2I) antibodyGTF2I 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-General Transcription Factor III (GTF2I) (AA 208-257) antibodyGTF2I 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠, Pig, Bat, 猴, Drosophila melanogaster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-General Transcription Factor III (GTF2I) (AA 600-810) antibodyGTF2I 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-General Transcription Factor III (GTF2I) (AA 956-985) antibodyGTF2I 适用: 人 WB, IHC, IF, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-General Transcription Factor III (GTF2I) (AA 1-976) antibodyGTF2I 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-General Transcription Factor III (GTF2I) (C-Term) antibodyGTF2I 适用: 人, 小鼠, 大鼠, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
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说明
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Related Products: ABIN968535, ABIN967389
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 250 μg/mL
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缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store undiluted at -20°C.
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: "BAP-135, a target for Bruton's tyrosine kinase in response to B cell receptor engagement." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 2, pp. 604-9, (1997) (PubMed).
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: "BAP-135, a target for Bruton's tyrosine kinase in response to B cell receptor engagement." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 2, pp. 604-9, (1997) (PubMed).
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- GTF2I (General Transcription Factor III (GTF2I))
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别名
- TFII-I
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背景
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General transcription factor II-I (GTF2I/TFII-I/SPIN/BAP-135) is a transcription factor that contains six directly repeated 90-residue regions, which possess helix-loop-helix protein-protein interaction motifs. TFII-I can regulate transcription in T-cells through interaction with the initiator elments (Inrs) within the AdML and Vbeta promoters, and associates with HIV-1, TdT, and ribonucleotide reductase R1 Inrs. In addition, TFII-I associates with the E box motif, the CACGTG sequence, and with serum response element sequences. The helix-loop-helix repeats facilitate TFII-I interaction with other transcription factors, such as USF, Myc, Phox 1, MADS box protein serum response factor, and STATs. TFII-I was also identified as Bruton's tyrosine kinase (btk)-associated protein (BAP-135). TFII-I/BAP-135 is tyrosine phosphorylated by btk and after EGF stimulation, and this phosphorylation enhances TFII-I transcriptional activity. The wide expression of TFII-I and the interaction of TFII-I with various Inrs and transcription factors implicates TFII-I in various signaling pathways that regulate gene transcription.
Synonyms: BAP-135 -
分子量
- 135/140 kDa
抗原
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