TEAD1 抗体 (AA 86-199)
(5 references)Quick Overview for TEAD1 抗体 (AA 86-199) (ABIN968252)
抗原
See all TEAD1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 86-199
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交叉反应
- 小鼠
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产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Human TEF-1 aa. 86-199
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亚型
- IgG1
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anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) (AA 135-215) antibody
TEAD1 适用: 人 WB, IHC, IF, ChIP 宿主: 兔 Polyclonal unconjugated
anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) (C-Term) antibodyTEAD1 适用: 人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 兔, 豚鼠, 马, Pig, 小鸡, 猴, Bat, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) (Internal Region) antibodyTEAD1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) (C-Term) antibodyTEAD1 适用: 人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 兔, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) (AA 135-215) antibodyTEAD1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) antibodyTEAD1 适用: 人 WB, ChIP, IP 宿主: 兔 Monoclonal unconjugated
anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) antibodyTEAD1 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) (AA 324-352), (C-Term) antibodyTEAD1 适用: 斑马鱼 WB 宿主: 兔 Polyclonal RB20896 unconjugated
anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) (N-Term) antibodyTEAD1 适用: 人, 小鼠, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) (AA 195-244) antibodyTEAD1 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 马, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 250 μg/mL
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缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store undiluted at -20°C.
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: "Identification of the functional domain in the transcription factor RTEF-1 that mediates alpha 1-adrenergic signaling in hypertrophied cardiac myocytes." in: The Journal of biological chemistry, Vol. 275, Issue 23, pp. 17476-80, (2000) (PubMed).
: "The human transcription enhancer factor-1, TEF-1, can substitute for Drosophila scalloped during wingblade development." in: The Journal of biological chemistry, Vol. 272, Issue 16, pp. 10664-8, (1997) (PubMed).
: "Transcription enhancer factor 1 interacts with a basic helix-loop-helix zipper protein, Max, for positive regulation of cardiac alpha-myosin heavy-chain gene expression." in: Molecular and cellular biology, Vol. 17, Issue 7, pp. 3924-36, (1997) (PubMed).
: "A novel family of developmentally regulated mammalian transcription factors containing the TEA/ATTS DNA binding domain." in: The Journal of biological chemistry, Vol. 271, Issue 36, pp. 21775-85, (1996) (PubMed).
: "Cloning, expression, and transcriptional properties of the human enhancer factor TEF-1." in: Cell, Vol. 65, Issue 4, pp. 551-68, (1991) (PubMed).
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: "Identification of the functional domain in the transcription factor RTEF-1 that mediates alpha 1-adrenergic signaling in hypertrophied cardiac myocytes." in: The Journal of biological chemistry, Vol. 275, Issue 23, pp. 17476-80, (2000) (PubMed).
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- TEAD1 (TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1))
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别名
- TEF-1
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背景
- TEF-1 (transcription enhancer factor-1) is a member of a family of transcription factors that contain an evolutionarily conserved DNA binding domain (DBD), TEA/ATTS. TEF-1 was identified as a HeLa cell transcriptional activator that bound, via its TEA domain, to the GT-IIC and Sph enhancer elements. Comparison of various enhancers indicates that TEF-1 binds to highly degenerate DNA sequences and cooperatively interacts with tandem repeats of its binding sites, which increases its enhancer activity. However, the DNA binding activities of TEF-1 are modulated by sequences outside the DBD. The N-terminal basic portion of TEF-1 contains the DBD. The C-terminal portion contains the transactivation domain and a zinc finger-like motif that is thought to be involved in protein dimerization or interaction with additional transcription factors. TEF-1 induced transcription requires a limiting transcriptional intermediary factor (TIF) and a TATA-binding protein associated factor (hTAFIIs). Although TEF-1 is expressed ubiquitously during embryogenesis, its expression is limited to adult kidney, heart, brain, skeletal muscle, and lungs. Disruption of murine TEF-1 gene results in fetal death.
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分子量
- 53 kDa
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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