BCAN 抗体 (AA 232-394)
(3 references)Quick Overview for BCAN 抗体 (AA 232-394) (ABIN968235)
抗原
See all BCAN 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 232-394
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交叉反应
- 小鼠, 犬
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产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Rat Brevican aa. 232-394
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亚型
- IgG1
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anti-Brevican (BCAN) (AA 23-353) antibody
BCAN 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Brevican (BCAN) (AA 219-655) antibody (PerCP)BCAN 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S294A-6 PerCP
anti-Brevican (BCAN) (AA 219-655) antibody (Atto 390)BCAN 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S294A-6 Atto 390
anti-Brevican (BCAN) (AA 219-655) antibodyBCAN 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S294A-6 unconjugated
anti-Brevican (BCAN) (AA 219-655) antibody (HRP)BCAN 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S294A-6 HRP
anti-Brevican (BCAN) (AA 219-655) antibody (FITC)BCAN 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S294A-6 FITC
anti-Brevican (BCAN) (AA 219-655) antibody (Biotin)BCAN 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S294A-6 Biotin
anti-Brevican (BCAN) (AA 219-655) antibody (PE)BCAN 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S294A-6 PE
anti-Brevican (BCAN) (AA 219-655) antibody (APC)BCAN 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S294A-6 APC
anti-Brevican (BCAN) (AA 219-655) antibody (Atto 594)BCAN 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S294A-6 Atto 594
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说明
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Related Products: ABIN968545, ABIN967389
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 250 μg/mL
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缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store undiluted at -20° C.
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: "The C-type lectin domains of lecticans, a family of aggregating chondroitin sulfate proteoglycans, bind tenascin-R by protein-protein interactions independent of carbohydrate moiety." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 19, pp. 10116-21, (1997) (PubMed).
: "Brevican, a chondroitin sulfate proteoglycan of rat brain, occurs as secreted and cell surface glycosylphosphatidylinositol-anchored isoforms." in: The Journal of biological chemistry, Vol. 270, Issue 45, pp. 27206-12, (1995) (PubMed).
: "Molecular cloning of brevican, a novel brain proteoglycan of the aggrecan/versican family." in: The Journal of biological chemistry, Vol. 269, Issue 13, pp. 10119-26, (1994) (PubMed).
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: "The C-type lectin domains of lecticans, a family of aggregating chondroitin sulfate proteoglycans, bind tenascin-R by protein-protein interactions independent of carbohydrate moiety." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 19, pp. 10116-21, (1997) (PubMed).
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- BCAN (Brevican (BCAN))
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别名
- Brevican
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背景
- Neural tissue expresses a variety of cell surface heparan sulfate and extracellular chondroitin sulfate containing proteoglycans. Brevican, a chondroitin sulfate proteoglycan, is a member of the lectican family. Other members of this family are aggrecan, versican, and neurocan. These proteins are either heparan sulfate or keratan sulfate containing glycosylphosphatidylinositol (GPI) anchored or membrane spanning proteoglycans, or soluble chondroitin sulfate containing proteoglycans. Brevican exists as either a soluble or GPI-anchored plasma membrane protein. Brevican contains the shortest core protein of any of the family members. In addition, it is characterized by chondroitin sulfate chains, an N-terminal hyaluronic acid-binding domain (HA), an epidermal growth factor-like (EGF) repeat, and lectin-like and complement regulatory protein-like domains in its C-terminal region. Primary cerebellar astrocytes are the major site for mRNA expression and little, if any, is found in neurons. Although there is an 80 kDa N-terminal truncated form, full length brevican can be up to 145 kDa. Brevican is thought to play a role in the terminal differentiation and regulation of the adult nervous system. This antibody is routinely tested by western blot analysis.
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分子量
- 140-145 kDa
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途径
- Glycosaminoglycan Metabolic Process
抗原
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