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SCARB1 抗体 (AA 104-294)

This anti-SCARB1 antibody is a 小鼠 单克隆 antibody detecting SCARB1 in WB 和 IF. Suitable for 人. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN968231
发货至: 中国

Quick Overview for SCARB1 抗体 (AA 104-294) (ABIN968231)

抗原

See all SCARB1 抗体
SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))

适用

  • 50
  • 31
  • 29
  • 2
  • 2
  • 2
  • 2
  • 1

宿主

  • 49
  • 9
  • 2
小鼠

克隆类型

  • 40
  • 20
单克隆

标记

  • 38
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
This SCARB1 antibody is un-conjugated

应用范围

  • 35
  • 19
  • 16
  • 12
  • 10
  • 10
  • 10
  • 8
  • 5
  • 4
  • 2
  • 1
  • 1
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  • 1
Western Blotting (WB), Immunofluorescence (IF)

克隆位点

25-CLA
  • 抗原表位

    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 104-294

    产品特性

    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    免疫原

    Human CLA-1 aa. 104-294

    亚型

    IgG1
  • 说明

    Related Products: ABIN968535, ABIN967389

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    250 μg/mL

    缓冲液

    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store undiluted at -20°C.
  • Lasley, Narayan, Uittenbogaard, Smart: "Activated cardiac adenosine A(1) receptors translocate out of caveolae." in: The Journal of biological chemistry, Vol. 275, Issue 6, pp. 4417-21, (2000) (PubMed).

    Kozarsky, Donahee, Rigotti, Iqbal, Edelman, Krieger: "Overexpression of the HDL receptor SR-BI alters plasma HDL and bile cholesterol levels." in: Nature, Vol. 387, Issue 6631, pp. 414-7, (1997) (PubMed).

    Acton, Rigotti, Landschulz, Xu, Hobbs, Krieger: "Identification of scavenger receptor SR-BI as a high density lipoprotein receptor." in: Science (New York, N.Y.), Vol. 271, Issue 5248, pp. 518-20, (1996) (PubMed).

    Calvo, Vega: "Identification, primary structure, and distribution of CLA-1, a novel member of the CD36/LIMPII gene family." in: The Journal of biological chemistry, Vol. 268, Issue 25, pp. 18929-35, (1993) (PubMed).

  • 抗原

    SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))

    别名

    CLA-1

    背景

    CLA-1 (CD36 and LIMPII Analogous-1) is member of a novel gene family that includes CD36, LIMPII, and SR-BI. CD36 is a cell surface glycoprotein that binds to collagen type I and thrombospondin. LIMPII (lysosomal integral membrane protein II), as its name suggests, is expressed on the membrane of lysosomes. SR-BI (scavenger receptor type B class I) is involved in the selective uptake of cholesterol esters. These proteins include two membrane-anchoring regions, two short cytoplasmic tails, and a large extracellular/luminal domain. CLA-1 mRNA is detected in a wide range of tissues including adrenal glands, liver, and testis. Its expression and similarity with other family members suggest it may play a role in HDL metabolism. However, identification of the CLA-1 receptor on monocytes indicates additional CLA-1 functions in leukocytes.
    Synonyms: CD36 and LIMPII Analogous-1

    分子量

    80 kDa

    途径

    Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Lipid Metabolism, SARS-CoV-2 Protein Interactome
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