Striatin 抗体 (AA 450-600)
(2 references)Quick Overview for Striatin 抗体 (AA 450-600) (ABIN968207)
抗原
See all Striatin (STRN) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 450-600
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交叉反应
- 小鼠, 人, 犬
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产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Rat Striatin aa. 450-600
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亚型
- IgG2b
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anti-Striatin (STRN) (AA 581-780) antibody
STRN 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Striatin (STRN) (C-Term) antibodySTRN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Striatin (STRN) (C-Term) antibodySTRN 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Striatin (STRN) (N-Term) antibodySTRN 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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说明
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Related Products: ABIN968545, ABIN967389
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 250 μg/mL
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缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store undiluted at -20° C.
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: "Zinedin, SG2NA, and striatin are calmodulin-binding, WD repeat proteins principally expressed in the brain." in: The Journal of biological chemistry, Vol. 275, Issue 26, pp. 19970-7, (2000) (PubMed).
: "A novel calmodulin-binding protein, belonging to the WD-repeat family, is localized in dendrites of a subset of CNS neurons." in: The Journal of cell biology, Vol. 134, Issue 4, pp. 1051-62, (1996) (PubMed).
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: "Zinedin, SG2NA, and striatin are calmodulin-binding, WD repeat proteins principally expressed in the brain." in: The Journal of biological chemistry, Vol. 275, Issue 26, pp. 19970-7, (2000) (PubMed).
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- Striatin (STRN)
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别名
- Striatin
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背景
- Signal transmission between neurons is regulated by the Ca2+-dependent release of neurotransmitters at the synapse. Striatin is a protein identified in the synaptosomal fraction of rat brain. Reports of sequence homology searches have shown that striatin belongs to a family of proteins with the repeated WD motif (the beta-transducin repeat or the WD-40 repeat) found in regulatory proteins. Striatin also binds calmodulin in a Ca2+-dependent manner. Immunolocalization and mRNA expression found striatin in the central nervous system, particularly enriched in neurons of the striatum and motor neurons. Furthermore, subcellular localization studies indicated that Striatin is tightly associated with the plasma membrane. Thus, striatin may play an important role in the Ca2+-dependent events occurring at the synapse.
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分子量
- 110 kDa
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途径
- Nuclear Hormone Receptor Binding, Cell-Cell Junction Organization
抗原
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