AKAP1 抗体 (AA 66-212)
(5 references)Quick Overview for AKAP1 抗体 (AA 66-212) (ABIN968136)
抗原
See all AKAP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 66-212
-
交叉反应
- 大鼠
-
产品特性
-
1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
-
免疫原
- Human AKAP149 aa. 66-212
-
亚型
- IgG1
-
-
anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) (AA 413-662) antibody
AKAP1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) (Internal Region) antibodyAKAP1 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) (AA 806-903) antibodyAKAP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) antibodyAKAP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) (AA 281-330) antibodyAKAP1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) (N-Term) antibodyAKAP1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) (AA 541-571) antibodyAKAP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) (AA 1-903) antibodyAKAP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) (C-Term) antibodyAKAP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
说明
-
Related Products: ABIN968535, ABIN967389
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 250 μg/mL
-
缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store undiluted at -20° C.
-
-
-
: "Identification and characterization of myeloid translocation gene 16b as a novel a kinase anchoring protein in T lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 4, pp. 1590-9, (2002) (PubMed).
: "A-kinase anchoring protein AKAP220 binds to glycogen synthase kinase-3beta (GSK-3beta ) and mediates protein kinase A-dependent inhibition of GSK-3beta." in: The Journal of biological chemistry, Vol. 277, Issue 40, pp. 36955-61, (2002) (PubMed).
: "Mistargeting of B-type lamins at the end of mitosis: implications on cell survival and regulation of lamins A/C expression." in: The Journal of cell biology, Vol. 153, Issue 3, pp. 621-6, (2001) (PubMed).
: "Protein kinase A anchoring." in: The Journal of biological chemistry, Vol. 272, Issue 20, pp. 12881-4, (1997) (PubMed).
: "Molecular characterization of AKAP149, a novel A kinase anchor protein with a KH domain." in: Biochemical and biophysical research communications, Vol. 225, Issue 1, pp. 313-9, (1996) (PubMed).
-
: "Identification and characterization of myeloid translocation gene 16b as a novel a kinase anchoring protein in T lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 4, pp. 1590-9, (2002) (PubMed).
-
- AKAP1 (A Kinase (PRKA) Anchor Protein 1 (AKAP1))
-
别名
- AKAP149
-
背景
- The targeting of protein kinases and phosphatases to cellular compartments in a timely manner may provide specificity in signal transduction events. For instance, attachment of type II cAMP-dependent Protein Kinase (PKA) to the cytoskeleton occurs through the binding of the regulatory subunit (RII) to microtubule associated-protein 2. Several proteins, such as microtubule-associated protein 2, have been identified as PKA type I/II anchoring proteins and form a family named AKAP (A-Kinase Anchor Proteins). AKAP149 is a protein of 903 amino acids. It has a PKA [RII] binding site at amino acids 355-376 preceded by a leucine zipper domain. AKAP149 mRNA has been reported to be expressed ubiquitously, with the highest levels in prostate and small intestine. AKAP149 contains a KH domain characteristic of RNA-binding proteins. Thus, AKAP149 is a PKA [RII] anchoring protein that may target this kinase to sites of RNA processing for regulation of RNA binding protein activity. This antibody is routinely tested by western blot analysis.
-
分子量
- 149 kDa
-
途径
- Synaptic Membrane
抗原
-
