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Liver Arginase 抗体 (AA 53-207)

Name: Liver Arginase 抗体 (AA 53-207)
SKU: ABIN968127
Availability: OutOfStock

This anti-Liver Arginase antibody is a 小鼠单克隆 antibody detecting Liver Arginase in WB, IHC, IF 和 IP. Suitable for 大鼠, 小鼠和 Blow Fly. This Primary Antibody has been cited in 5+ publications.

Western blot analysis of Arginase I on a mouse liver lysate. (Liver Arginase 抗体 (AA 53-207))

Immunofluorescence staining of mouse macrophages. (Liver Arginase 抗体 (AA 53-207))

2 images

(5 references)

产品编号 ABIN968127

发货至: 中国

Datasheet as PDF

Quick Overview for Liver Arginase 抗体 (AA 53-207) (ABIN968127)

抗原

See all Liver Arginase (ARG1) 抗体

Liver Arginase (ARG1) (Arginase, Liver (ARG1))

适用

大鼠, 小鼠, Blow Fly

宿主

小鼠

克隆类型

单克隆

标记

This Liver Arginase antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

克隆位点

19-Arginase I

Discover our top product ARG1 Primary Antibody

抗原表位
32

27

16

13

9

7

7

6

5

4

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 53-207

交叉反应

小鼠, 大鼠, Fruit Fly (Drosophila melanogaster)

产品特性

1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

纯化方法

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

免疫原

Human Arginase I aa. 53-207

亚型

IgG1
anti-Arginase, Liver (ARG1) antibody
KO Validated ARG1 适用: 人 WB, ELISA, FACS, IHC (p), IF, IP, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Arginase, Liver (ARG1) (AA 11-97) antibody
ARG1 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal ARG1-1125 unconjugated

anti-Arginase, Liver (ARG1) (C-Term) antibody
ARG1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Arginase, Liver (ARG1) (C-Term) antibody
Verified ARG1 适用: 人, 大鼠, 小鼠, Pig WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

anti-Arginase, Liver (ARG1) (C-Term) antibody
Verified ARG1 适用: 大鼠, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Arginase, Liver (ARG1) (N-Term) antibody
ARG1 适用: 人, 大鼠, 小鼠, Cow, 兔, 犬, Pig, 马, 山羊, 豚鼠, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Arginase, Liver (ARG1) (AA 293-322) antibody
ARG1 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Arginase, Liver (ARG1) (AA 151-220) antibody
ARG1 适用: 人, 大鼠 ELISA, FACS, IHC (p), ICC, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Arginase, Liver (ARG1) (AA 1-322) antibody
ARG1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Arginase, Liver (ARG1) (N-Term) antibody
ARG1 适用: 人, 大鼠, 小鼠, Cow, 兔, 犬, Pig, 马, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

说明

Related Products: ABIN968543, ABIN967389

限制

仅限研究用
状态

Liquid

浓度

250 μg/mL

缓冲液

Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store undiluted at -20° C.
Morrison, Correll: "Activation of the stem cell-derived tyrosine kinase/RON receptor tyrosine kinase by macrophage-stimulating protein results in the induction of arginase activity in murine peritoneal macrophages." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 2, pp. 853-60, (2002) (PubMed).

Chang, Zoghi, Liao, Kuo: "The involvement of tyrosine kinases, cyclic AMP/protein kinase A, and p38 mitogen-activated protein kinase in IL-13-mediated arginase I induction in macrophages: its implications in IL-13-inhibited nitric oxide production." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 4, pp. 2134-41, (2000) (PubMed).

Sonoki, Nagasaki, Gotoh, Takiguchi, Takeya, Matsuzaki, Mori: "Coinduction of nitric-oxide synthase and arginase I in cultured rat peritoneal macrophages and rat tissues in vivo by lipopolysaccharide." in: The Journal of biological chemistry, Vol. 272, Issue 6, pp. 3689-93, (1997) (PubMed).

Dizikes, Grody, Kern, Cederbaum: "Isolation of human liver arginase cDNA and demonstration of nonhomology between the two human arginase genes." in: Biochemical and biophysical research communications, Vol. 141, Issue 1, pp. 53-9, (1987) (PubMed).

Haraguchi, Takiguchi, Amaya, Kawamoto, Matsuda, Mori: "Molecular cloning and nucleotide sequence of cDNA for human liver arginase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 84, Issue 2, pp. 412-5, (1987) (PubMed).
抗原

Liver Arginase (ARG1) (Arginase, Liver (ARG1))

别名

Arginase I

背景

Arginase converts arginine into urea plus ornithine, the final step in urea synthesis. Two different isoforms (I&II) have been isolated with approximately 60% homology at the nucleotide level. While type II is present in many tissues, Arginase I is expressed exclusively in liver. In cultured macrophages, as well as in vivo, Arginase I is induced with nitric oxide synthase (NOS) and the arginase I transactivator C/EBPbeta in response to lipopolysaccharide. This response occurs in a dose and time-dependent manner. While the mRNA for NOS appears as early as 2h after treatment, mRNA levels for arginase I peak after twelve hours of lipopolysaccharide treatment. Since the synthesis of nitric oxide by NOS requires arginine, the delayed induction of arginase I may be necessary for the regulation of NOS activity. This antibody is routinely tested by western blot analysis.

分子量

35 kDa

途径

Cellular Response to Molecule of Bacterial Origin