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Annexin VII 抗体 (AA 34-159)

There are 5+ publications for this product available. The 小鼠 单克隆 anti-Annexin VII antibody is suitable to detect Annexin VII in samples from 人. It has been validated for WB, IHC, IF 和 IP.
产品编号 ABIN968099
发货至: 中国
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Quick Overview for Annexin VII 抗体 (AA 34-159) (ABIN968099)

抗原

See all Annexin VII (ANXA7) 抗体
Annexin VII (ANXA7) (Annexin A7 (ANXA7))

适用

  • 104
  • 47
  • 38
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人

宿主

  • 102
  • 4
  • 1
小鼠

克隆类型

  • 72
  • 35
单克隆

标记

  • 44
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
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  • 1
  • 1
  • 1
  • 1
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  • 1
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This Annexin VII antibody is un-conjugated

应用范围

  • 97
  • 64
  • 34
  • 32
  • 32
  • 17
  • 13
  • 13
  • 13
  • 8
  • 3
  • 1
  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

克隆位点

5-Annexin VII
  • 抗原表位

    • 15
    • 13
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    AA 34-159

    产品特性

    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    免疫原

    Human Annexin VII aa. 34-159

    亚型

    IgG1
  • 说明

    Related Products: ABIN968536, ABIN967389

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    250 μg/mL

    缓冲液

    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store undiluted at -20° C.
  • Salzer, Hinterdorfer, Hunger, Borken, Prohaska: "Ca(++)-dependent vesicle release from erythrocytes involves stomatin-specific lipid rafts, synexin (annexin VII), and sorcin." in: Blood, Vol. 99, Issue 7, pp. 2569-77, (2002) (PubMed).

    Srivastava, Bubendorf, Srikantan, Fossom, Nolan, Glasman, Leighton, Fehrle, Pittaluga, Raffeld, Koivisto, Willi, Gasser, Kononen, Sauter, Kallioniemi, Srivastava, Pollard: "ANX7, a candidate tumor suppressor gene for prostate cancer." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 8, pp. 4575-80, (2001) (PubMed).

    Furge, Chen, Cohen: "Annexin VII and annexin XI are tyrosine phosphorylated in peroxovanadate-treated dogs and in platelet-derived growth factor-treated rat vascular smooth muscle cells." in: The Journal of biological chemistry, Vol. 274, Issue 47, pp. 33504-9, (1999) (PubMed).

    Selbert, Fischer, Pongratz, Stewart, Noegel: "Expression and localization of annexin VII (synexin) in muscle cells." in: Journal of cell science, Vol. 108 ( Pt 1), pp. 85-95, (1995) (PubMed).

    Magendzo, Shirvan, Cultraro, Srivastava, Pollard, Burns: "Alternative splicing of human synexin mRNA in brain, cardiac, and skeletal muscle alters the unique N-terminal domain." in: The Journal of biological chemistry, Vol. 266, Issue 5, pp. 3228-32, (1991) (PubMed).

  • 抗原

    Annexin VII (ANXA7) (Annexin A7 (ANXA7))

    别名

    Annexin VII

    背景

    Annexin VII, also known as synexin, is a member of the Annexin family characterized by Ca2+ dependent phospholipid binding. Annexins have a four-fold internal repeat of about 70 amino acids that contains the Ca2+-binding sites. They also have a regulatory NH2-terminal region of 30-40 amino acids. Annexin VII mRNA has been detected in many tissues and is most abundant in brain, heart, skeletal muscle, and lung. Annexin VII mRNA exhibits a tissue dependent polymorphism due to alternative splicing which results in two different isoforms of 47 kDa and 51 kDa. In vitro, Annexin VII aggregates chromaffin granules and enhances membrane fusion in a Ca2+ and GTP-dependent manner. Although the physiological role of Annexin VII is not completely understood, it is believed to influence and regulate Ca2+ dependent events such as secretion at the plasma membrane.
    Synonyms: Synexin

    分子量

    51 kDa
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