Sec8 抗体 (AA 31-201)
(3 references)-
- 抗原 See all Sec8 (EXOC4) 抗体
- Sec8 (EXOC4) (Exocyst Complex Component 4 (EXOC4))
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抗原表位
- AA 31-201
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适用
- 人, 小鼠, 大鼠, 犬, 小鸡
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Sec8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
- 交叉反应
- 犬, 小鼠, 小鸡, 人
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Rat Sec8 aa. 31-201
- 克隆位点
- 14-Sec8
- 亚型
- IgG2b
- Top Product
- Discover our top product EXOC4 Primary Antibody
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anti-Exocyst Complex Component 4 (EXOC4) (AA 1-109) antibody
EXOC4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4F1 unconjugated
anti-Exocyst Complex Component 4 (EXOC4) (AA 239-273), (N-Term) antibodyEXOC4 适用: 人 WB 宿主: 兔 Polyclonal RB52634 unconjugated
anti-Exocyst Complex Component 4 (EXOC4) (N-Term) antibodyEXOC4 适用: 人, 小鼠, 大鼠, Pig, 兔, Cow, 马, 斑马鱼, 小鸡, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Exocyst Complex Component 4 (EXOC4) (AA 71-120) antibodyEXOC4 适用: 人, 小鼠, 大鼠, Pig, 兔, Cow, 马, 小鸡, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Exocyst Complex Component 4 (EXOC4) (AA 1-280) antibodyEXOC4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 说明
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Related Products: ABIN968619, ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20° C.
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: "Compromised cytoarchitecture and polarized trafficking in autosomal dominant polycystic kidney disease cells." in: The Journal of cell biology, Vol. 149, Issue 1, pp. 111-24, (2000) (PubMed).
: "High-efficiency Semliki Forest virus-mediated transduction in bovine adrenal chromaffin cells." in: The Biochemical journal, Vol. 342 Pt 3, pp. 497-501, (1999) (PubMed).
: "rSec6 and rSec8, mammalian homologs of yeast proteins essential for secretion." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 21, pp. 9613-7, (1995) (PubMed).
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: "Compromised cytoarchitecture and polarized trafficking in autosomal dominant polycystic kidney disease cells." in: The Journal of cell biology, Vol. 149, Issue 1, pp. 111-24, (2000) (PubMed).
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- 抗原
- Sec8 (EXOC4) (Exocyst Complex Component 4 (EXOC4))
- 别名
- Sec8 (EXOC4 产品)
- 别名
- CG2095 antibody, Dmel\\CG2095 antibody, Sec8 antibody, Sec8p antibody, dsec8 antibody, fun antibody, SEC8L1 antibody, DKFZp459N1430 antibody, SEC8 antibody, C78892 antibody, Sec8l1 antibody, ALR antibody, si:ch211-92l17.2 antibody, si:rp71-18a24.2 antibody, ATSEC8 antibody, SUBUNIT OF EXOCYST COMPLEX 8 antibody, subunit of exocyst complex 8 antibody, Secretory 8 antibody, exocyst complex component 4 antibody, exocyst complex component 4 L homeolog antibody, Exocyst complex component 4 antibody, subunit of exocyst complex 8 antibody, Sec8 antibody, EXOC4 antibody, CpipJ_CPIJ001354 antibody, Exoc4 antibody, exoc4 antibody, exoc4.L antibody, sec-8 antibody, SEC8 antibody
- 背景
- Signal transmission between neurons is regulated by the release of neurotransmitters at the synapse. This process, which is controlled by a complex pathway of membrane trafficking in the presynaptic nerve terminal, leads to membrane fusion and neurotransmitter secretion. Sec8 is a hydrophilic protein of 975 amino acids that is highly expressed in brain and kidney. It is homologus with the yeast secretory protein, Sec8p. In yeast, Sec8 is essential for the Golgi-to-plasma membrane traffic of proteins during constitutive secretion. In rat brain, Sec8 colocalizes with Rab3 and Syntaxin-1a, two important proteins that regulate the fusion of the synaptic vesicle to the plasma membrane. The primary structure of Sec8, a coiled-coil domain (residues 34-99), is commonly found in other proteins important in secretory pathways. This antibody is routinely tested by western blot analysis.
- 分子量
- 110 kDa
- 途径
- Peptide Hormone Metabolism, Synaptic Vesicle Exocytosis
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