FKBP10 抗体 (AA 434-576)
(2 references)Quick Overview for FKBP10 抗体 (AA 434-576) (ABIN968087)
抗原
See all FKBP10 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 434-576
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交叉反应
- 大鼠, 人
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产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Please refer to us for technical protocols. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Mouse FKBP65 aa. 434-576
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亚型
- IgG1
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anti-FK506 Binding Protein 10, 65 KDa (FKBP10) (AA 377-470) antibody
FKBP10 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D4 unconjugated
anti-FK506 Binding Protein 10, 65 KDa (FKBP10) (AA 377-470) antibodyFKBP10 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B5 unconjugated
anti-FK506 Binding Protein 10, 65 KDa (FKBP10) (AA 552-580), (C-Term) antibodyFKBP10 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19280 unconjugated
anti-FK506 Binding Protein 10, 65 KDa (FKBP10) (AA 316-573) antibodyFKBP10 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 10, 65 KDa (FKBP10) (AA 377-470) antibodyFKBP10 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-FK506 Binding Protein 10, 65 KDa (FKBP10) (AA 158-440) antibodyFKBP10 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 10, 65 KDa (FKBP10) (AA 57-87) antibodyFKBP10 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19279 unconjugated
anti-FK506 Binding Protein 10, 65 KDa (FKBP10) (AA 57-87), (N-Term) antibodyFKBP10 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 10, 65 KDa (FKBP10) (AA 303-582) antibodyFKBP10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 10, 65 KDa (FKBP10) (AA 65-94), (N-Term) antibodyFKBP10 适用: 人, 小鼠 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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说明
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Related Products: ABIN967389, ABIN968539
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 250 μg/mL
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缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store undiluted at -20°C.
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: "Developmental regulation of FKBP65. An ER-localized extracellular matrix binding-protein." in: Molecular biology of the cell, Vol. 11, Issue 11, pp. 3925-35, (2001) (PubMed).
: "Molecular cloning, DNA sequence analysis, and biochemical characterization of a novel 65-kDa FK506-binding protein (FKBP65)." in: The Journal of biological chemistry, Vol. 270, Issue 49, pp. 29336-41, (1996) (PubMed).
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: "Developmental regulation of FKBP65. An ER-localized extracellular matrix binding-protein." in: Molecular biology of the cell, Vol. 11, Issue 11, pp. 3925-35, (2001) (PubMed).
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- FKBP10 (FK506 Binding Protein 10, 65 KDa (FKBP10))
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别名
- FKBP65
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背景
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FK506, one of multiple potent compounds that block T cell proliferation, is used for immunosuppressive therapy. Several FK506-binding proteins (FKBPs) have been identified in the search for intracellular targets for FK506. These include FKBP12, FKBP13, FKBP51, and FKBP52. The immunosuppressive effects of FK506 and FKBPs result from the inhibition of the calcineurin phosphatase, a well known component of the signaling cascade leading to IL-2 production. FKBP65 is another member of the FKBP protein family and contains the characteristic peptidylprolyl cis-trans-isomerase activity. FKBP65 has been reported to be expressed in the lung, testis, brain, heart, and spleen. Although it has a predicted molecular weight of 65 kDa, FKBP65 has been observed to migrate ranging from 68-72 kDa in SDS electrophoresis gels, perhaps, due to glycosylation and/or phosphorylation.
Synonyms: FK506 Binding Protein-65 -
分子量
- 68-72 kDa
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途径
- SARS-CoV-2 Protein Interactome
抗原
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