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MVP 抗体 (AA 403-592)

Name: MVP 抗体 (AA 403-592)
SKU: ABIN968013
Availability: OutOfStock

This anti-MVP antibody is a 小鼠单克隆 antibody detecting MVP in WB, IHC, IF 和 IP. Suitable for 人, Cow, 兔和犬. This Primary Antibody has been cited in 5+ publications.

Western blot analysis of LRP on human endothelial lysate. (MVP 抗体 (AA 403-592))

Immunofluorescence staining of Rabbit Kidney (MVP 抗体 (AA 403-592))

Image no. 3 for anti-Major Vault Protein (MVP) (AA 403-592) antibody (ABIN968013) (MVP 抗体 (AA 403-592))

Western Blotting (WB) image for anti-Major Vault Protein (MVP) (AA 403-592) antibody (ABIN968013) (MVP 抗体 (AA 403-592))

4 images

(5 references)

产品编号 ABIN968013

发货至: 中国

Quick Overview for MVP 抗体 (AA 403-592) (ABIN968013)

抗原

See all MVP 抗体

MVP (Major Vault Protein (MVP))

适用

人, Cow, 兔, 犬

宿主

小鼠

克隆类型

单克隆

标记

This MVP antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

克隆位点

42-LRP

Discover our top product MVP Primary Antibody

抗原表位
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AA 403-592

交叉反应

牛, 犬, 兔

产品特性

1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

纯化方法

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

免疫原

Human LRP aa. 403-592

亚型

IgG1
anti-Major Vault Protein (MVP) (AA 1-893) antibody
MVP 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2H3-1A6 unconjugated

anti-Major Vault Protein (MVP) (AA 2-272) antibody
MVP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Major Vault Protein (MVP) antibody
MVP 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Major Vault Protein (MVP) antibody
KO Validated MVP 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Major Vault Protein (MVP) (AA 2-259) antibody
MVP 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, ELISA, IF, IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated

anti-Major Vault Protein (MVP) antibody
MVP 适用: 人, 小鼠, 大鼠 WB, FACS, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Major Vault Protein (MVP) (AA 88-180) antibody
MVP 适用: 人, 斑马鱼 FACS, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-Major Vault Protein (MVP) antibody
MVP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Major Vault Protein (MVP) antibody
MVP 适用: 人 FACS, IF 宿主: 小鼠 Monoclonal 1014 unconjugated

anti-Major Vault Protein (MVP) (C-Term) antibody
KO Validated MVP 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

说明

Related Products: ABIN967389, ABIN968536

限制

仅限研究用
状态

Liquid

浓度

250 μg/mL

缓冲液

Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store undiluted at -20°C.
Papura: "Managed care policy regarding OMT reimbursement illogical." in: The Journal of the American Osteopathic Association, Vol. 102, Issue 2, pp. 66, (2002) (PubMed).

Rybarova, Batekova, Hodorova, Mirossay, Kluchova, Bobrov, Kocisova: "Immunohistochemical detection of LRP protein in the normal human lung." in: Bratislavské lekárske listy, Vol. 102, Issue 2, pp. 66-72, (2001) (PubMed).

List, Spier, Grogan, Johnson, Roe, Greer, Wolff, Broxterman, Scheffer, Scheper, Dalton: "Overexpression of the major vault transporter protein lung-resistance protein predicts treatment outcome in acute myeloid leukemia." in: Blood, Vol. 87, Issue 6, pp. 2464-9, (1996) (PubMed).

Kickhoefer, Rome: "The sequence of a cDNA encoding the major vault protein from Rattus norvegicus." in: Gene, Vol. 151, Issue 1-2, pp. 257-60, (1995) (PubMed).

Scheffer, Wijngaard, Flens, Izquierdo, Slovak, Pinedo, Meijer, Clevers, Scheper: "The drug resistance-related protein LRP is the human major vault protein." in: Nature medicine, Vol. 1, Issue 6, pp. 578-82, (1995) (PubMed).
抗原

MVP (Major Vault Protein (MVP))

别名

LRP

背景

Drugs that selectively attack dividing cells are often used in cancer therapy. However, small cell populations do not die, but develop resistance to a variety of toxic drugs. Multidrug resistance is achieved by gene amplification of specific membrane-bound transport ATPases that shuttle the drugs out of cells. Some multidrug-resistant cancer cells express a protein of 110 kDa named LRP (Lung Resistance-related Protein). LRP expression might be an indicator of prognosis after chemotherapy in acute myeloid leukemia and ovarian carcinoma. The LRP gene encodes a protein of 896 amino acids with significant homology to the major vault protein from Dictyostelium discoideum. Although ubiquitously expressed, LRP is most abundant in epithelial cells.

分子量

110 kDa