SNAP91 抗体 (AA 706-896)
(5 references)Quick Overview for SNAP91 抗体 (AA 706-896) (ABIN967993)
抗原
See all SNAP91 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 706-896
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交叉反应
- 小鼠, 人
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产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Rat AP180 aa. 706-896
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亚型
- IgG1
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anti-Synaptosomal-Associated Protein 91 (SNAP91) (AA 279-297) antibody
SNAP91 适用: 人, 大鼠, 小鼠, 犬 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Synaptosomal-Associated Protein 91 (SNAP91) antibodySNAP91 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Synaptosomal-Associated Protein 91 (SNAP91) (AA 156-255) antibodySNAP91 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Synaptosomal-Associated Protein 91 (SNAP91) (AA 201-300) antibodySNAP91 适用: 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Synaptosomal-Associated Protein 91 (SNAP91) antibodySNAP91 适用: 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Synaptosomal-Associated Protein 91 (SNAP91) (AA 1-907) antibodySNAP91 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Synaptosomal-Associated Protein 91 (SNAP91) (AA 321-600) antibodySNAP91 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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说明
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Related Products: ABIN968545, ABIN967389
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store undiluted at -20° C.
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: "Clint: a novel clathrin-binding ENTH-domain protein at the Golgi." in: Molecular biology of the cell, Vol. 13, Issue 11, pp. 4060-73, (2002) (PubMed).
: "Interaction of two structurally distinct sequence types with the clathrin terminal domain beta-propeller." in: The Journal of biological chemistry, Vol. 276, Issue 31, pp. 28700-9, (2001) (PubMed).
: "Crystal structure of the alpha appendage of AP-2 reveals a recruitment platform for clathrin-coat assembly." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 16, pp. 8907-12, (1999) (PubMed).
: "Clathrin binding and assembly activities of expressed domains of the synapse-specific clathrin assembly protein AP-3." in: The Journal of biological chemistry, Vol. 270, Issue 18, pp. 10933-9, (1995) (PubMed).
: "Clathrin assembly protein AP180: primary structure, domain organization and identification of a clathrin binding site." in: The EMBO journal, Vol. 12, Issue 2, pp. 667-75, (1993) (PubMed).
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: "Clint: a novel clathrin-binding ENTH-domain protein at the Golgi." in: Molecular biology of the cell, Vol. 13, Issue 11, pp. 4060-73, (2002) (PubMed).
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- SNAP91 (Synaptosomal-Associated Protein 91 (SNAP91))
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别名
- AP180
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背景
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AP180, also known as AP-3, F1-20, NP185, and pp155, is one of four assembly proteins which are involved in the organization and assembly of clathrin triskelia in clathrin-coated vesicles. Two of these proteins, AP-1 and AP-2, exist as tetramers, while AP180 and auxilin are monomeric assembly proteins. The clathrin binding potential of AP180 is defined by several regions of the molecule, including the 30 kDa N-terminal domain, a central domain, and a 58 kDa C-terminal domain. Although clathrin binding occurs throughout the molecule, only the C-terminal domain is associated with both binding of clathrin and assembly of clathrin cages. The highly acidic central domain, which contains an uncharged alanine-rich segment, is thought to impart the irregular physical properties to this protein. AP180 is the only clathrin assembly protein specific for synapses and is thought to be involved in synaptic vesicle biogenesis and recycling. Furthermore, AP180 is bound by inositol-6-phosphate which has been shown to be closely regulated in neuronal cells by external stimuli.
Synonyms: AP-3, F1-20, NP185, and pp155 -
分子量
- 180 kDa
抗原
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