Kalinin B1 (AA 1009-1170) 抗体
适用: 犬, 人
IF, IP, IHC, WB
宿主: 小鼠
Monoclonal
17-Kalinin B1
unconjugated
(3 references)-
- 抗原
- Kalinin B1
- 抗原表位
- AA 1009-1170
- 适用
- 犬, 人
- 宿主
- 小鼠
- 克隆类型
- 单克隆
- 应用范围
- Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
- 交叉反应
- 犬
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human Kalinin B1 aa. 1009-1170
- 克隆位点
- 17-Kalinin B1
- 亚型
- IgG1
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- 说明
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Related Products: ABIN967389, ABIN968536
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20°C.
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: "Laminin-6 is activated by proteolytic processing and regulates cellular adhesion and migration differently from laminin-5." in: The Journal of biological chemistry, Vol. 277, Issue 51, pp. 49287-95, (2002) (PubMed).
: "Structural requirement of carboxyl-terminal globular domains of laminin alpha 3 chain for promotion of rapid cell adhesion and migration by laminin-5." in: The Journal of biological chemistry, Vol. 275, Issue 29, pp. 22495-502, (2000) (PubMed).
: "The complete primary structure for a novel laminin chain, the laminin B1k chain." in: The Journal of biological chemistry, Vol. 269, Issue 15, pp. 11073-80, (1994) (PubMed).
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: "Laminin-6 is activated by proteolytic processing and regulates cellular adhesion and migration differently from laminin-5." in: The Journal of biological chemistry, Vol. 277, Issue 51, pp. 49287-95, (2002) (PubMed).
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- 抗原
- Kalinin B1
- 背景
- Kalinin is an epithelial cell laminin. It is a structural component of the dermal-epidermal junction of skin and basement membrane. The full molecule is composed of a 200 kDa A subunit, a 155 kDa B2 subunit, and a 140 kDa B1 subunit. Another B1k subunit with a predicted molecular weight of 126.9 kDa is encoded by a 3.9kb gene. The apparent molecular weight of Kalinin B1k is 140 kDa due to glycosylation. Its structure is divided into a long arm and a short arm domain that bind and crosslink with the other kalinin subunits.
- 分子量
- 140 kDa
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