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HSP90 抗体 (AA 586-732)

HSP90 适用: 人, 大鼠, 小鼠, 小鸡, 犬 WB, IP, IHC, IF 宿主: 小鼠 Monoclonal 68-Hsp90 unconjugated
产品编号 ABIN967958
发货至: 中国
  • 抗原 See all HSP90 抗体
    HSP90 (Heat Shock Protein 90 (HSP90))
    抗原表位
    • 10
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 586-732
    适用
    • 106
    • 58
    • 56
    • 28
    • 23
    • 20
    • 20
    • 19
    • 11
    • 10
    • 10
    • 10
    • 9
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠, 小鸡, 犬
    宿主
    • 84
    • 63
    • 2
    • 1
    小鼠
    克隆类型
    • 86
    • 64
    单克隆
    标记
    • 53
    • 12
    • 11
    • 10
    • 10
    • 10
    • 9
    • 9
    • 8
    • 8
    • 4
    • 4
    • 2
    This HSP90 antibody is un-conjugated
    应用范围
    • 131
    • 89
    • 88
    • 67
    • 47
    • 45
    • 31
    • 20
    • 10
    • 10
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    小鼠, 大鼠, 犬, 小鸡
    产品特性
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Human Hsp90 aa. 586-732
    克隆位点
    68-Hsp90
    亚型
    IgG1
    Top Product
    Discover our top product HSP90 Primary Antibody
  • 说明

    Related Products: ABIN968535, ABIN967389

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    250 μg/mL
    缓冲液
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store undiluted at -20°C.
  • Murata, Suzuki, Yamawaki, Sato, Hori, Karaki, Ozaki: "Dexamethasone prevents impairment of endothelium-dependent relaxation in arteries cultured with fetal bovine serum." in: European journal of pharmacology, Vol. 515, Issue 1-3, pp. 134-41, (2005) (PubMed).

    Miyamoto, Nakayama, Imaki, Hirose, Jiang, Abe, Tsukiyama, Nagahama, Ohno, Hatakeyama, Nakayama: "Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cdelta." in: Nature, Vol. 416, Issue 6883, pp. 865-9, (2002) (PubMed).

    Murata, Sato, Hori, Ozaki, Karaki: "Decreased endothelial nitric-oxide synthase (eNOS) activity resulting from abnormal interaction between eNOS and its regulatory proteins in hypoxia-induced pulmonary hypertension." in: The Journal of biological chemistry, Vol. 277, Issue 46, pp. 44085-92, (2002) (PubMed).

    Brouet, Sonveaux, Dessy, Balligand, Feron: "Hsp90 ensures the transition from the early Ca2+-dependent to the late phosphorylation-dependent activation of the endothelial nitric-oxide synthase in vascular endothelial growth factor-exposed endothelial cells." in: The Journal of biological chemistry, Vol. 276, Issue 35, pp. 32663-9, (2001) (PubMed).

    Pritchard, Ackerman, Gross, Stepp, Shi, Fontana, Baker, Sessa: "Heat shock protein 90 mediates the balance of nitric oxide and superoxide anion from endothelial nitric-oxide synthase." in: The Journal of biological chemistry, Vol. 276, Issue 21, pp. 17621-4, (2001) (PubMed).

    Rebbe, Ware, Bertina, Modrich, Stafford: "Nucleotide sequence of a cDNA for a member of the human 90-kDa heat-shock protein family." in: Gene, Vol. 53, Issue 2-3, pp. 235-45, (1987) (PubMed).

  • 抗原
    HSP90 (Heat Shock Protein 90 (HSP90))
    别名
    Hsp90 (HSP90 产品)
    背景
    The 90 kDa heat shock protein (Hsp90), a highly conserved stress-induced protein, is abundantly expressed in most tissues under nonstress conditions and is required for eukaryotic cell viability. Hsp90 interacts with a number of signaling molecules, other heat shock proteins, and cytoskeletal proteins. However, the function of Hsp90 in these complexes remains unclear. It is thought that Hsp90 plays a common role in a number of diverse signaling systems due to its physical association with v-Src family tyrosine kinases, steroid hormone receptors, the Raf serine/threonine kinase, the basic-helix-loop-helix dioxin receptor, and the betagamma subunits of G proteins.
    Synonyms: Heat Shock Protein-90
    分子量
    90 kDa
    途径
    M Phase, Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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