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Cadherin 4 抗体 (AA 22-201)

This anti-Cadherin 4 antibody is a 小鼠 单克隆 antibody detecting Cadherin 4 in WB, IHC 和 IP. Suitable for 小鼠 和 大鼠. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN967954
发货至: 中国

Quick Overview for Cadherin 4 抗体 (AA 22-201) (ABIN967954)

抗原

See all Cadherin 4 (CDH4) 抗体
Cadherin 4 (CDH4)

适用

  • 63
  • 23
  • 9
  • 5
  • 5
  • 2
  • 2
  • 1
  • 1
小鼠, 大鼠

宿主

  • 59
  • 5
  • 1
小鼠

克隆类型

  • 60
  • 5
单克隆

标记

  • 28
  • 6
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Cadherin 4 antibody is un-conjugated

应用范围

  • 53
  • 22
  • 21
  • 18
  • 13
  • 13
  • 12
  • 11
  • 9
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

克隆位点

48-R
  • 抗原表位

    • 15
    • 10
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
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    • 1
    AA 22-201

    交叉反应

    大鼠

    产品特性

    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    免疫原

    Mouse R-Cadherin aa. 22-201

    亚型

    IgG2a kappa
  • 说明

    Related Products: ABIN968545, ABIN967389

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    250 μg/mL

    缓冲液

    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store undiluted at -20°C.
  • Tanihara, Sano, Heimark, St John, Suzuki: "Cloning of five human cadherins clarifies characteristic features of cadherin extracellular domain and provides further evidence for two structurally different types of cadherin." in: Cell adhesion and communication, Vol. 2, Issue 1, pp. 15-26, (1995) (PubMed).

    Hutton, Christofori, Chi, Edman, Guest, Hanahan, Kelly: "Molecular cloning of mouse pancreatic islet R-cadherin: differential expression in endocrine and exocrine tissue." in: Molecular endocrinology (Baltimore, Md.), Vol. 7, Issue 9, pp. 1151-60, (1994) (PubMed).

    Matsunami, Miyatani, Inoue, Copeland, Gilbert, Jenkins, Takeichi: "Cell binding specificity of mouse R-cadherin and chromosomal mapping of the gene." in: Journal of cell science, Vol. 106 ( Pt 1), Issue 6, pp. 401-9, (1994) (PubMed).

  • 抗原

    Cadherin 4 (CDH4)

    别名

    R-Cadherin

    背景

    R-Cadherin was first isolated from chicken retina, but was subsequently shown to be present and highly conserved in a variety of tissues from several different species. A 913 amino acid polypeptide, R-Cadherin is highly homologous to Cadherin-4, but is most closely related to another family member, N-Cadherin. In experiments using chimeric L cells expressing chicken or mouse Cadherins, those cells expressing mouse or chicken R-Cadherin were able to aggregate with each other as well as with cells expressing N-Cadherin. However, there was no aggregation of R-Cadherin expressing cells, with P- or E-Cadherin expressing cells. This suggests that the roles of specific cadherins are conserved among types in the determination of heterogenous cell segregation and distribution during tissue morphogenesis and maintenance.

    分子量

    100 kDa

    途径

    Cell-Cell Junction Organization, Regulation of Cell Size
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