ANXA6 抗体 (AA 1-673)
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北京 101111
Quick Overview for ANXA6 抗体 (AA 1-673) (ABIN967890)
抗原
See all ANXA6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-673
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交叉反应
- 大鼠
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产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Human Annexin VI aa. 1-673
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亚型
- IgG1
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说明
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Related Products: ABIN968537, ABIN967389
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 250 μg/mL
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缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store undiluted at -20°C.
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: "Identification of novel markers for monitoring minimal residual disease in acute lymphoblastic leukemia." in: Blood, Vol. 97, Issue 7, pp. 2115-20, (2001) (PubMed).
: "Annexins in cell membrane dynamics. Ca(2+)-regulated association of lipid microdomains." in: The Journal of cell biology, Vol. 150, Issue 5, pp. 1113-24, (2000) (PubMed).
: "Annexin VI participates in the formation of a reversible, membrane-cytoskeleton complex in smooth muscle cells." in: The Journal of biological chemistry, Vol. 274, Issue 49, pp. 35191-5, (2000) (PubMed).
: "Phosphatidylinositide 3-kinase localizes to cytoplasmic lipid bodies in human polymorphonuclear leukocytes and other myeloid-derived cells." in: Blood, Vol. 95, Issue 3, pp. 1078-85, (2000) (PubMed).
: "Diversity in the lipocortin/calpactin family." in: Cell, Vol. 55, Issue 1, pp. 1-3, (1988) (PubMed).
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- ANXA6 (Annexin A6 (ANXA6))
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别名
- Annexin VI
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背景
- Annexins are a widely expressed family of Ca[2+] and phospholipid-binding proteins. At least ten have been identified in mammalian tissues. They have also been identified in Drosophila, Hydra, and Dictyostelium. Annexin VI is a 70 kDa member of the annexin family. While most of the other annexin family members have a four amino acid sequence repeat, Annexin VI displays an eight residue repeat. It is a widely expressed protein, found in lymphocytes, neurons, and many other cell types. Work on annexins has addressed the possible role of Annexin VI in various stages of the endocytic pathway. Some studies suggest that Annexin VI is required for coated-vesicle budding. However, other research directly contradicts this data. Thus, the role of Annexin VI is still under investigation.
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分子量
- 70 kDa
抗原
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