RAB5 抗体 (AA 1-215)
(5 references)Quick Overview for RAB5 抗体 (AA 1-215) (ABIN967882)
抗原
See all RAB5 (RAB5A) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-215
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交叉反应
- 大鼠, 小鼠
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产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Human Rab5 aa. 1-215
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亚型
- IgG1
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anti-RAB5A, Member RAS Oncogene Family (RAB5A) (C-Term) antibody
RAB5A 适用: 人, 小鼠, 大鼠, Cow, 猴, 犬, 绵羊, 马, 兔, 豚鼠, Pig, Hamster, 小鸡, Avian, Cat, 驴, 山羊 WB, IF, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-RAB5A, Member RAS Oncogene Family (RAB5A) (C-Term) antibodyRAB5A 适用: 人, 小鼠, 大鼠, Cow, 猴, 犬, 绵羊, 马, 兔, 豚鼠, Pig, Hamster, 小鸡, Avian, Cat, 驴, 山羊 WB, IF 宿主: 山羊 Polyclonal unconjugated
anti-RAB5A, Member RAS Oncogene Family (RAB5A) antibodyRAB5A 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RAB5A, Member RAS Oncogene Family (RAB5A) (AA 1-215) antibodyRAB5A 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 3H5C11 unconjugated
anti-RAB5A, Member RAS Oncogene Family (RAB5A) (AA 1-215) antibodyRAB5A 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-RAB5A, Member RAS Oncogene Family (RAB5A) antibody (Atto 390)RAB5A 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal Atto 390
anti-RAB5A, Member RAS Oncogene Family (RAB5A) (AA 182-211) antibodyRAB5A 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-RAB5A, Member RAS Oncogene Family (RAB5A) antibody (Biotin)RAB5A 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal Biotin
anti-RAB5A, Member RAS Oncogene Family (RAB5A) antibody (PE)RAB5A 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal PE
anti-RAB5A, Member RAS Oncogene Family (RAB5A) antibody (APC)RAB5A 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal APC
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说明
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Related Products: ABIN968536, ABIN967389
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 250 μg/mL
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缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store undiluted at -20° C.
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: "Insulin can regulate GLUT4 internalization by signaling to Rab5 and the motor protein dynein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 23, pp. 13084-9, (2001) (PubMed).
: "Rim1 and rabphilin-3 bind Rab3-GTP by composite determinants partially related through N-terminal alpha -helix motifs." in: The Journal of biological chemistry, Vol. 276, Issue 35, pp. 32480-8, (2001) (PubMed).
: "Entry and trafficking of granzyme B in target cells during granzyme B-perforin-mediated apoptosis." in: Blood, Vol. 92, Issue 3, pp. 1044-54, (1998) (PubMed).
: "Structure-function relationship of the small GTPase rab5." in: The Journal of biological chemistry, Vol. 268, Issue 32, pp. 24475-80, (1993) (PubMed).
: "Prenylation of Rab5 is dependent on guanine nucleotide binding." in: The Journal of biological chemistry, Vol. 268, Issue 32, pp. 23773-6, (1993) (PubMed).
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: "Insulin can regulate GLUT4 internalization by signaling to Rab5 and the motor protein dynein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 23, pp. 13084-9, (2001) (PubMed).
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- RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))
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别名
- Rab5
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背景
- Rab5 is a low molecular weight GTP-binding protein that plays a role in endocytic vesicle traffic. Like other Rab proteins, Rab5 has C-terminal cysteine residues that are post-translationally modified by geranylgeranylation, which is critical for its membrane targeting. Rab5 is associated with early endosome and plasma membranes and evidence suggests that Rab5 is involved in regulation of early endosome fusion. The GTP/GDP cycle controls shuttling of Rab proteins between the cytosol and organelle membranes. In vitro, Rab5 proteins are removed from membranes by a GDP dissociation inhibitor protein (rabGDI) which leads to the formation of a cytosolic Rab5-rabGDI complex. Rab5 insertion into membranes is a multistep process in which a transient GDP-Rab5 intermediate is formed and converted into GTP-Rab5 that subsequently enters the acceptor membrane and releases rabGDI into the cytosol.
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分子量
- 25 kDA
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途径
- Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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