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CAMK4 抗体 (AA 1-241)

Name: CAMK4 抗体 (AA 1-241)
SKU: ABIN967876
Availability: OutOfStock

This anti-CAMK4 antibody is a 小鼠单克隆 antibody detecting CAMK4 in WB, IHC, IF 和 IP. Suitable for 人, 小鼠和大鼠. This Primary Antibody has been cited in 5+ publications.

Western blot analysis of CaM Kinase IV on Jurkat lysate. (CAMK4 抗体 (AA 1-241))

Immunofluorescent staining on WI38 cells. (CAMK4 抗体 (AA 1-241))

Pyrimidal cells in rat cortex, formalin-fixed paraffin embedded tissue, no pre-treatment, 20X (CAMK4 抗体 (AA 1-241))

IHC (p)

3 images

(5 references)

产品编号 ABIN967876

发货至: 中国

Datasheet as PDF

Quick Overview for CAMK4 抗体 (AA 1-241) (ABIN967876)

抗原

See all CAMK4 抗体

CAMK4 (Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4))

适用

人, 小鼠, 大鼠

宿主

小鼠

克隆类型

单克隆

标记

This CAMK4 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

克隆位点

26-CaM Kinase IV

Discover our top product CAMK4 Primary Antibody

抗原表位
23

16

7

7

6

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

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1

1

1

1

1

1
AA 1-241

交叉反应

小鼠, 大鼠

产品特性

1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

纯化方法

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

免疫原

Human CaM Kinase IV aa. 1-241

亚型

IgG1
anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 1-473) antibody
CAMK4 适用: 人 WB, ELISA, IF, IHC (p), RNAi 宿主: 小鼠 Monoclonal 1A3 unconjugated

anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 35-292) antibody
CAMK4 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 8C5B8 unconjugated

anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 304-473) antibody
CAMK4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 35-292) antibody
CAMK4 适用: 人 WB, ELISA, IHC, IF/ICC, FACS 宿主: 小鼠 Monoclonal unconjugated

anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (pThr200) antibody
CAMK4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 1-473) antibody
CAMK4 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 304-473) antibody
CAMK4 适用: 人 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated

anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 1-474) antibody
CAMK4 适用: 人 WB, ELISA, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1A3 unconjugated

anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 1-473) antibody
CAMK4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) antibody
CAMK4 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

说明

Related Products: ABIN968537, ABIN967389

限制

仅限研究用
状态

Liquid

浓度

250 μg/mL

缓冲液

Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store undiluted at -20°C.
Wei, Qiu, Liauw, Robinson, Ho, Chatila, Zhuo: "Calcium calmodulin-dependent protein kinase IV is required for fear memory." in: Nature neuroscience, Vol. 5, Issue 6, pp. 573-9, (2002) (PubMed).

Slee, Adrain, Martin: "Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis." in: The Journal of biological chemistry, Vol. 276, Issue 10, pp. 7320-6, (2001) (PubMed).

Passier, Zeng, Frey, Naya, Nicol, McKinsey, Overbeek, Richardson, Grant, Olson: "CaM kinase signaling induces cardiac hypertrophy and activates the MEF2 transcription factor in vivo." in: The Journal of clinical investigation, Vol. 105, Issue 10, pp. 1395-406, (2000) (PubMed).

Wayman, Walters, Kolibaba, Soderling, Christian: "CaM kinase IV regulates lineage commitment and survival of erythroid progenitors in a non-cell-autonomous manner." in: The Journal of cell biology, Vol. 151, Issue 4, pp. 811-24, (2000) (PubMed).

Ohmstede, Bland, Merrill, Sahyoun: "Relationship of genes encoding Ca2+/calmodulin-dependent protein kinase Gr and calspermin: a gene within a gene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 13, pp. 5784-8, (1991) (PubMed).
抗原

CAMK4 (Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4))

别名

CaM Kinase IV

背景

CaM-kinase IV (Ca2+/calmodulin-dependent protein kinase IV, also described as CaM-kinase Gr) is activated through the binding of Ca2+/CaM and by phosphorylation. This kinase has high sequence homologies with the catalytic and regulatory domains of CaM-kinase II. CaM-kinase IV is a monomer which is highly expressed in cerebellum, thymus, and testis. Its subcellular distrubution includes localization in both the synaptic regions of the molecular layer of the cerebellum, and the nuclei of cerebellar granule cells. CaM-kinase IV has an autoinhibitory domain within residues 305-321 that can suppress kinase activity in the absence of Ca2+/CaM. This type of domain is common in many other CaM-dependent kinases and phosphatases. CaM-kinase IV does not appear to be significantly activated by autophosphorylation, but it can be activated approximately 5-10-fold when phosphorylated by CaM-kinase IV kinase.

分子量

60 kDa

途径

EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Production of Molecular Mediator of Immune Response, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma