RBP4 抗体 (AA 1-135)
(5 references)-
- 抗原 See all RBP4 抗体
- RBP4 (Retinol Binding Protein 4, Plasma (RBP4))
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抗原表位
- AA 1-135
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适用
- 人, 小鼠, 大鼠, 小鸡, 犬
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This RBP4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
- 交叉反应
- 犬, 小鸡, 小鼠, 大鼠
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human RBP aa. 1-135
- 克隆位点
- 42-RBP
- 亚型
- IgG1
- Top Product
- Discover our top product RBP4 Primary Antibody
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anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 63-245) antibody
RBP4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) antibodyRBP4 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) antibodyRBP4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) antibodyRBP4 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 4C2 unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) antibodyRBP4 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal A9 unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) antibodyRBP4 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 19-201) antibodyRBP4 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 19-201) antibodyRBP4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 18-201) antibodyRBP4 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C4 unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 19-201) antibodyRBP4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E3 unconjugated
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- 说明
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Related Products: ABIN967389, ABIN968619
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20°C.
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: "Evidence for an essential role of megalin in transepithelial transport of retinol." in: Journal of the American Society of Nephrology : JASN, Vol. 10, Issue 4, pp. 685-95, (1999) (PubMed).
: "Crystal structure of liganded and unliganded forms of bovine plasma retinol-binding protein." in: The Journal of biological chemistry, Vol. 268, Issue 15, pp. 10728-38, (1993) (PubMed).
: "The interaction of N-ethyl retinamide with plasma retinol-binding protein (RBP) and the crystal structure of the retinoid-RBP complex at 1.9-A resolution." in: The Journal of biological chemistry, Vol. 268, Issue 33, pp. 24873-9, (1993) (PubMed).
: "Crystal structure of the trigonal form of human plasma retinol-binding protein at 2.5 A resolution." in: Journal of molecular biology, Vol. 230, Issue 2, pp. 613-24, (1993) (PubMed).
: "Transport and storage of vitamin A." in: Science (New York, N.Y.), Vol. 250, Issue 4979, pp. 399-404, (1990) (PubMed).
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: "Evidence for an essential role of megalin in transepithelial transport of retinol." in: Journal of the American Society of Nephrology : JASN, Vol. 10, Issue 4, pp. 685-95, (1999) (PubMed).
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- 抗原
- RBP4 (Retinol Binding Protein 4, Plasma (RBP4))
- 别名
- RBP (RBP4 产品)
- 别名
- RDCCAS antibody, RBP antibody, RNBP antibody, rbp4 antibody, MGC54038 antibody, srbp antibody, PRBP antibody, RBPA antibody, Rbp-4 antibody, fb23c12 antibody, rbp antibody, wu:fb23c12 antibody, wu:fb58d04 antibody, wu:fb72b04 antibody, zgc:86911 antibody, retinol binding protein 4 antibody, renin binding protein antibody, retinol binding protein 4 S homeolog antibody, retinol binding protein 4 A, plasma antibody, retinol binding protein 4, plasma antibody, retinol binding protein 4 L homeolog antibody, RBP4 antibody, RENBP antibody, rbp4.S antibody, rbp4 antibody, Rbp4 antibody, RBP4A antibody, rbp4.L antibody
- 背景
- Retinol, a metabolic precursor of retinal and retinoic acid, is transported in plasma bound to a carrier protein known as retinol-binding protein (RBP). RBP is the only retinoid-specific binding protein that has been identified in plasma. The presence of RBP increases the stability of retinol as it is transported from its stores to target cells. In plasma, the 21 kDa RBP forms a tight complex with thyroxine-binding transthyretin (TTR), a homotetramer of about 55 kDa. Association of RBP with TTR increases the stability of the retinol-RBP complex. It is believed that this association prevents filtration of the relatively small RBP through the kidney glomeruli. Once retinol is delivered to its target cells, the resulting retinol-free RBP has a reduced affinity for TTR and thus can be selectively cleared from the circulation by filtration through kidney glomeruli. The three dimensional structures of human and bovine RBP have been compared and appear to be very similar.
- 分子量
- 21 kDa
- 途径
- Regulatory RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
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