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P-Cadherin 抗体 (AA 72-259)

Name: P-Cadherin 抗体 (AA 72-259)
SKU: ABIN967839
Availability: OutOfStock

This anti-P-Cadherin antibody is a 小鼠单克隆 antibody detecting P-Cadherin in WB, IHC, IF 和 IP. Suitable for 人和大鼠. This Primary Antibody has been cited in 5+ publications.

Western blot analysis of P-Cadherin on A431 cell lysate. (P-Cadherin 抗体 (AA 72-259))

Immunofluorescent staining of A431 cells. (P-Cadherin 抗体 (AA 72-259))

2 images

(5 references)

产品编号 ABIN967839

发货至: 中国

Datasheet as PDF

Quick Overview for P-Cadherin 抗体 (AA 72-259) (ABIN967839)

抗原

See all P-Cadherin (CDH3) 抗体

P-Cadherin (CDH3)

适用

人, 大鼠

宿主

小鼠

克隆类型

单克隆

标记

This P-Cadherin antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

克隆位点

56-P

Discover our top product CDH3 Primary Antibody

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AA 72-259

交叉反应

大鼠

产品特性

1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

纯化方法

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

免疫原

Human P-Cadherin aa. 72-259

亚型

IgG1
anti-P-Cadherin (CDH3) (AA 371-660) antibody
CDH3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-P-Cadherin (CDH3) (N-Term) antibody
CDH3 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-P-Cadherin (CDH3) (AA 625-725) antibody
CDH3 适用: 人, 小鼠 WB, ELISA, FACS, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-P-Cadherin (CDH3) (AA 24-350) antibody
CDH3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-P-Cadherin (CDH3) (C-Term) antibody
CDH3 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

anti-P-Cadherin (CDH3) (AA 117-360) antibody
CDH3 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-P-Cadherin (CDH3) (AA 1-829) antibody
CDH3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-P-Cadherin (CDH3) (AA 1-829) antibody
CDH3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-P-Cadherin (CDH3) (AA 187-236) antibody
CDH3 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-P-Cadherin (CDH3) (AA 612-626), (Middle Region) antibody
CDH3 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

说明

Related Products: ABIN968533, ABIN967389

限制

仅限研究用
状态

Liquid

浓度

250 μg/mL

缓冲液

Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store undiluted at -20°C.
Holsinger, Ward, Duffield, Zachwieja, Jallal: "The transmembrane receptor protein tyrosine phosphatase DEP1 interacts with p120(ctn)." in: Oncogene, Vol. 21, Issue 46, pp. 7067-76, (2002) (PubMed).

Bailey, Biddlestone, Shepherd, Barr, Warner, Jankowski: "Altered cadherin and catenin complexes in the Barrett's esophagus-dysplasia-adenocarcinoma sequence: correlation with disease progression and dedifferentiation." in: The American journal of pathology, Vol. 152, Issue 1, pp. 135-44, (1998) (PubMed).

Kantak, Kramer: "E-cadherin regulates anchorage-independent growth and survival in oral squamous cell carcinoma cells." in: The Journal of biological chemistry, Vol. 273, Issue 27, pp. 16953-61, (1998) (PubMed).

Tao, Edwards, Tubb, Wang, Bryan, McCrea: "beta-Catenin associates with the actin-bundling protein fascin in a noncadherin complex." in: The Journal of cell biology, Vol. 134, Issue 5, pp. 1271-81, (1996) (PubMed).

Nose, Nagafuchi, Takeichi: "Isolation of placental cadherin cDNA: identification of a novel gene family of cell-cell adhesion molecules." in: The EMBO journal, Vol. 6, Issue 12, pp. 3655-61, (1988) (PubMed).
抗原

P-Cadherin (CDH3)

别名

P-Cadherin

背景

Cadherins are a family of transmembrane glycoproteins involved in the Ca2+-dependent cell-cell adhesion that occurs in many tissues. Cadherins are similar in their domain structure, Ca2+ and protease sensitivity, and molecular weight. However, these proteins have distinct tissue expression patterns and immunological reactivities. P-Cadherin is localized in placenta while E-Cadherin and N-Cadherin are found in epithelial and neural tissues, respectively. P-Cadherin is an 829 amino acid polypeptide with a putative signal peptide and precursor region, an extracellular domain containing several internal repeats, and a highly hydrophobic transmembrane region. The cytoplasmic domain provides a link to the cytoskeleton through the associated catenin proteins.

分子量

120 kDa