CNTNAP1 抗体 (AA 1-1513)
(5 references)Quick Overview for CNTNAP1 抗体 (AA 1-1513) (ABIN967781)
抗原
See all CNTNAP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 1-1513
-
交叉反应
- 犬, 大鼠, 小鼠, 小鸡, Frog
-
产品特性
-
1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
-
免疫原
- Human p190 aa. 1-1513
-
亚型
- IgG1
-
-
anti-Contactin Associated Protein 1 (CNTNAP1) (AA 20-300) antibody
CNTNAP1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Contactin Associated Protein 1 (CNTNAP1) (AA 151-250) antibodyCNTNAP1 适用: 人 WB, ELISA, FACS, ICC, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Contactin Associated Protein 1 (CNTNAP1) (AA 26-356) antibodyCNTNAP1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Contactin Associated Protein 1 (CNTNAP1) (AA 20-300) antibodyCNTNAP1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Contactin Associated Protein 1 (CNTNAP1) (AA 926-1190) antibodyCNTNAP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Contactin Associated Protein 1 (CNTNAP1) (AA 673-918) antibodyCNTNAP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Contactin Associated Protein 1 (CNTNAP1) antibodyCNTNAP1 适用: 大鼠 WB, IHC, IP, FM 宿主: 小鼠 Monoclonal S65-35 unconjugated
anti-Contactin Associated Protein 1 (CNTNAP1) (AA 22-131) antibodyCNTNAP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Contactin Associated Protein 1 (CNTNAP1) (AA 72-121) antibodyCNTNAP1 适用: 人, 犬, Cow, 豚鼠, 马, 兔, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Contactin Associated Protein 1 (CNTNAP1) antibodyCNTNAP1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
-
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 250 μg/mL
-
缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store undiluted at -20°C.
-
-
-
: "RhoA is required for cortical retraction and rigidity during mitotic cell rounding." in: The Journal of cell biology, Vol. 160, Issue 2, pp. 255-65, (2003) (PubMed).
: "p190RhoGAP can act to inhibit PDGF-induced gliomas in mice: a putative tumor suppressor encoded on human chromosome 19q13.3." in: Genes & development, Vol. 17, Issue 4, pp. 476-87, (2003) (PubMed).
: "Protein kinase C induces actin reorganization via a Src- and Rho-dependent pathway." in: The Journal of biological chemistry, Vol. 277, Issue 23, pp. 20903-10, (2002) (PubMed).
: "Activation of beta1 integrin signaling stimulates tyrosine phosphorylation of p190RhoGAP and membrane-protrusive activities at invadopodia." in: The Journal of biological chemistry, Vol. 273, Issue 1, pp. 9-12, (1998) (PubMed).
: "Molecular cloning of cDNAs encoding the GAP-associated protein p190: implications for a signaling pathway from ras to the nucleus." in: Cell, Vol. 69, Issue 3, pp. 539-49, (1992) (PubMed).
-
: "RhoA is required for cortical retraction and rigidity during mitotic cell rounding." in: The Journal of cell biology, Vol. 160, Issue 2, pp. 255-65, (2003) (PubMed).
-
- CNTNAP1 (Contactin Associated Protein 1 (CNTNAP1))
-
别名
- p190
-
背景
- GTPase activating proteins (GAPs) stimulate the GTP-hydrolyzing activity of GTPases, such as p21[ ras]. Ras-GAP (120kDa) is perhaps the best characterized GAP. p190 is a Ras-GAP associated protein that is tyrosine phosphorylated in transformed and growth factor-stimulated cells. Ras-GAP and p190 are targets of oncoproteins and growth factor receptors. Recombinant p190 enhances GTPase activity of the rho family of GTPases. The complete sequence of p190 exhibits three major regions: an N-terminal region with homology to all GTPases, a middle region homologous to transcriptional repressors, and a C-terminal region the is similar to n-chimerin and other small GTPases.
-
分子量
- 190 kDa
-
途径
- Cell-Cell Junction Organization
抗原
-
