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Annexin A2 抗体 (AA 1-97)

There are 5+ publications for this product available. The 小鼠 单克隆 anti-Annexin A2 antibody is suitable to detect Annexin A2 in samples from 人, 小鼠, 大鼠, 犬 和 小鸡. It has been validated for WB, IHC, IF 和 IP.
产品编号 ABIN967724
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Annexin A2 抗体 (AA 1-97) (ABIN967724)

抗原

See all Annexin A2 (ANXA2) 抗体
Annexin A2 (ANXA2)

适用

  • 151
  • 87
  • 76
  • 5
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  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, 犬, 小鸡

宿主

  • 126
  • 29
  • 3
  • 1
小鼠

克隆类型

  • 98
  • 61
单克隆

标记

  • 79
  • 13
  • 9
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This Annexin A2 antibody is un-conjugated

应用范围

  • 118
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  • 41
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  • 23
  • 15
  • 14
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

克隆位点

148-Annexin II Light Chain
  • 抗原表位

    • 20
    • 15
    • 13
    • 12
    • 6
    • 6
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    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-97

    交叉反应

    犬, 小鸡, 人

    无交叉反应

    大鼠, 小鼠

    产品特性

    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    免疫原

    Cow Annexin II Light Chain aa. 1-97

    亚型

    IgG1
  • 说明

    Related Products: ABIN968536, ABIN967389

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    250 μg/mL

    缓冲液

    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store undiluted at -20°C.
  • Huang, Pawliczak, Cowan, Gladwin, Madara, Logun, Shelhamer: "Epidermal growth factor induces p11 gene and protein expression and down-regulates calcium ionophore-induced arachidonic acid release in human epithelial cells." in: The Journal of biological chemistry, Vol. 277, Issue 41, pp. 38431-40, (2002) (PubMed).

    Kwon, Caplan, Filipenko, Choi, Fitzpatrick, Zhang, Waisman: "Identification of annexin II heterotetramer as a plasmin reductase." in: The Journal of biological chemistry, Vol. 277, Issue 13, pp. 10903-11, (2002) (PubMed).

    Choi, Fitzpatrick, Filipenko, Fogg, Kassam, Magliocco, Waisman: "Regulation of plasmin-dependent fibrin clot lysis by annexin II heterotetramer." in: The Journal of biological chemistry, Vol. 276, Issue 27, pp. 25212-21, (2001) (PubMed).

    Harder, Kellner, Parton, Gruenberg: "Specific release of membrane-bound annexin II and cortical cytoskeletal elements by sequestration of membrane cholesterol." in: Molecular biology of the cell, Vol. 8, Issue 3, pp. 533-45, (1997) (PubMed).

    Regnouf, Sagot, Delouche, Devilliers, Cartaud, Henry, Pradel: ""In vitro" phosphorylation of annexin 2 heterotetramer by protein kinase C. Comparative properties of the unphosphorylated and phosphorylated annexin 2 on the aggregation and fusion of chromaffin granule membranes." in: The Journal of biological chemistry, Vol. 270, Issue 45, pp. 27143-50, (1995) (PubMed).

  • 抗原

    Annexin A2 (ANXA2)

    别名

    Annexin II

    背景

    Annexin II often exists as a heterotetramer complexed with an 11kDa light chain. This p11 subunit is related to the S100 family of calcium-binding proteins but mutations have rendered it unable to bind calcium. The p11 protein binds to the amino terminus of the annexin II monomer, but not to other annexins. It may regulate the function of annexin II, as the tetrameric form seems to have a higher calcium and phospholipid-binding affinity than the monomeric annexin II. In the cell, p11 has been localized to the cytoplasmic face of the plasma membrane where the annexin II tetramer is known to exist.

    分子量

    11 kDa

    途径

    S100 Proteins
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