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Annexin A2 抗体 (AA 123-328)

Name: Annexin A2 抗体 (AA 123-328)
SKU: ABIN967722
Availability: OutOfStock

Cited in 5+ publications. The 小鼠单克隆 anti-Annexin A2 antibody (Clone 5-Annexin II) (ABIN967722) specifically detects Annexin A2 in WB, IF, IP 和 IHC (f). The antibody is reactive with 人, 小鼠, 大鼠, 犬和小鸡 samples.

Western blot analysis of Annexin II on a A431 lysate. (Annexin A2 抗体 (AA 123-328))

Immunofluorescence staining of human fibroblasts. (Annexin A2 抗体 (AA 123-328))

Image no. 2 for anti-Annexin A2 (ANXA2) (AA 123-328) antibody (ABIN967722) (Annexin A2 抗体 (AA 123-328))

Western Blotting (WB) image for anti-Annexin A2 (ANXA2) (AA 123-328) antibody (ABIN967722) (Annexin A2 抗体 (AA 123-328))

4 images

(5 references)

产品编号 ABIN967722

发货至: 中国

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中国
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Quick Overview for Annexin A2 抗体 (AA 123-328) (ABIN967722)

抗原

See all Annexin A2 (ANXA2) 抗体

Annexin A2 (ANXA2)

适用

人, 小鼠, 大鼠, 犬, 小鸡

宿主

小鼠

克隆类型

单克隆

标记

This Annexin A2 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

5-Annexin II

Discover our top product ANXA2 Primary Antibody

抗原表位
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2

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1
AA 123-328

交叉反应

小鸡, 犬, 小鼠, 大鼠

产品特性

1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

纯化方法

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

免疫原

Human Annexin II aa. 123-328

亚型

IgG1
anti-Annexin A2 (ANXA2) (AA 19-49), (N-Term) antibody
ANXA2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB15421 unconjugated

anti-Annexin A2 (ANXA2) (AA 1-357) antibody
ANXA2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Annexin A2 (ANXA2) (AA 1-339) antibody
ANXA2 适用: 人 WB, IF, RNAi 宿主: 小鼠 Monoclonal 3E8-B6 unconjugated

anti-Annexin A2 (ANXA2) (AA 19-357) antibody
ANXA2 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 1G7 unconjugated

anti-Annexin A2 (ANXA2) (AA 2-339) antibody
ANXA2 适用: 人 WB, IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Annexin A2 (ANXA2) (N-Term) antibody
KO Validated ANXA2 适用: 人 WB, IF, IP, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Annexin A2 (ANXA2) (AA 1-339) antibody
ANXA2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Annexin A2 (ANXA2) (AA 287-313), (C-Term) antibody
ANXA2 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB15467 unconjugated

anti-Annexin A2 (ANXA2) (AA 1-339) antibody
ANXA2 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Annexin A2 (ANXA2) antibody
ANXA2 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 1A1E1 unconjugated

说明

Related Products: ABIN968533, ABIN967389

限制

仅限研究用
状态

Liquid

浓度

250 μg/mL

缓冲液

Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store undiluted at -20° C.
Hansen, Ehrlich, Nelson: "Molecular mechanism for orienting membrane and actin dynamics to nascent cell-cell contacts in epithelial cells." in: The Journal of biological chemistry, Vol. 277, Issue 47, pp. 45371-6, (2002) (PubMed).

Kwon, Caplan, Filipenko, Choi, Fitzpatrick, Zhang, Waisman: "Identification of annexin II heterotetramer as a plasmin reductase." in: The Journal of biological chemistry, Vol. 277, Issue 13, pp. 10903-11, (2002) (PubMed).

Choi, Fitzpatrick, Filipenko, Fogg, Kassam, Magliocco, Waisman: "Regulation of plasmin-dependent fibrin clot lysis by annexin II heterotetramer." in: The Journal of biological chemistry, Vol. 276, Issue 27, pp. 25212-21, (2001) (PubMed).

Jacovina, Zhong, Khazanova, Lev, Deora, Hajjar: "Neuritogenesis and the nerve growth factor-induced differentiation of PC-12 cells requires annexin II-mediated plasmin generation." in: The Journal of biological chemistry, Vol. 276, Issue 52, pp. 49350-8, (2001) (PubMed).

Chasserot-Golaz, Vitale, Sagot, Delouche, Dirrig, Pradel, Henry, Aunis, Bader: "Annexin II in exocytosis: catecholamine secretion requires the translocation of p36 to the subplasmalemmal region in chromaffin cells." in: The Journal of cell biology, Vol. 133, Issue 6, pp. 1217-36, (1996) (PubMed).
抗原

Annexin A2 (ANXA2)

别名

Annexin II

背景

Annexin II (p36), originally discovered as a substrate for the src oncogene, is one of the most studied members of the annexin family of calcium-dependent phospholipid-binding proteins. It exists in cells as either a monomer or a heterotetramer complexed with p11, an S100-related protein. In vitro, it has been found that unphosphorylated annexin II is capable of causing aggregation of chromaffin granules, and, upon phosphorylation, induces fusion of the granules' membranes. A similiar phenomenon may occur in the final steps of exocytosis after cytoplasmic annexin translocates to the subplasmalemmal region and is phosphorylated by protein kinase C. However, other studies refute annexin II's involvement in exocytosis, and a conclusive role for annexin II in membrane trafficking remains debated. This antibody is routinely tested by western blot analysis.
Synonyms: Lipocortin II, Calpactin I

分子量

36 kDa

途径

S100 Proteins