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SOX17 抗体

This anti-SOX17 antibody is a 小鼠 单克隆 antibody detecting SOX17 in WB, IF, BI 和 ICS. Suitable for 人. This Primary Antibody has been cited in 6+ publications.
产品编号 ABIN967681
发货至: 中国

Quick Overview for SOX17 抗体 (ABIN967681)

抗原

See all SOX17 抗体
SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))

适用

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宿主

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小鼠

克隆类型

  • 43
  • 11
单克隆

标记

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This SOX17 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), BioImaging (BI), Intracellular Staining (ICS)

克隆位点

P7-969
  • 品牌

    BD Pharmingen™

    产品特性

    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. An isotype control should be used at the same concentration as the antibody of interest.
    3. Please refer to us for technical protocols.
    4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    5. Sodium azide is a reversible inhibitor of oxidative metabolism, therefore, antibody preparations containing this preservative agent must not be used in cell cultures nor injected into animals. Sodium azide may be removed by washing stained cells or plate-bound antibody or dialyzing soluble antibody in sodium azide-free buffer. Since endotoxin may also affect the results of functional studies, we recommend the NA/LE (No Azide/Low Endotoxin) antibody format, if available, for in vitro and in vivo use.
    6. Triton is a trademark of the Dow Chemical Company.

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    免疫原

    Human Sox17 Recombinant Protein

    亚型

    IgG1 kappa
  • 说明

    Related Products: ABIN967389

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Aqueous buffered solution containing ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C.
  • Serrano, Gandillet, Pearson, Lacaud, Kouskoff: "Contrasting effects of Sox17- and Sox18-sustained expression at the onset of blood specification." in: Blood, Vol. 115, Issue 19, pp. 3895-8, (2010) (PubMed).

    Séguin, Draper, Nagy, Rossant: "Establishment of endoderm progenitors by SOX transcription factor expression in human embryonic stem cells." in: Cell stem cell, Vol. 3, Issue 2, pp. 182-95, (2008) (PubMed).

    Kim, Saunders, Morrison: "Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells." in: Cell, Vol. 130, Issue 3, pp. 470-83, (2007) (PubMed).

    DAmour, Agulnick, Eliazer, Kelly, Kroon, Baetge: "Efficient differentiation of human embryonic stem cells to definitive endoderm." in: Nature biotechnology, Vol. 23, Issue 12, pp. 1534-41, (2005) (PubMed).

    Collet, Secombes: "Construction and analysis of a secreting expression vector for fish cells." in: Vaccine, Vol. 23, Issue 13, pp. 1534-9, (2005) (PubMed).

    Katoh: "Molecular cloning and characterization of human SOX17." in: International journal of molecular medicine, Vol. 9, Issue 2, pp. 153-7, (2002) (PubMed).

  • 抗原

    SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))

    别名

    SOX17

    背景

    The P7-969 monoclonal antibody reacts with human Sox17, a member of the SOX (SRY-releated HMG-box) family of transcription factors. SOX family members contain a DNA binding domain (HMG-box) and are involved in the control of development. Sox17 is expressed in primitive and definitive endoderm and regulates fetal and neonatal hematopoietic stem cell proliferation.
    Synonyms: SOX-17, SOX17, FLJ22252

    分子量

    45 kDa

    基因ID

    64321
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