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SOX2 抗体

Cited in 3+ publications. This 小鼠 单克隆 anti-SOX2 antibody (Clone O30-678) specifically detects SOX2 in WB, IF, ICS 和 BI. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN967676
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SOX2 抗体 (ABIN967676)

抗原

See all SOX2 抗体
SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

适用

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人, 小鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This SOX2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Intracellular Staining (ICS), BioImaging (BI)

克隆位点

O30-678
  • 交叉反应

    小鼠

    产品特性

    1. Please refer to us for technical protocols.
    2. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. mTESR™1 is a trademark of StemCell Technologies.
    5. Triton is a trademark of the Dow Chemical Company.
    6. Alexa Fluor® is a registered trademark of Life Technologies Corporation.

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    免疫原

    Human Sox2 Recombinant Protein

    亚型

    IgG1 kappa
  • 说明

    Related Products: ABIN967389

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Aqueous buffered solution containing ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C.
  • Pan, Thomson: "Nanog and transcriptional networks in embryonic stem cell pluripotency." in: Cell research, Vol. 17, Issue 1, pp. 42-9, (2007) (PubMed).

    Takahashi, Yamanaka: "Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors." in: Cell, Vol. 126, Issue 4, pp. 663-76, (2006) (PubMed).

    Boyer, Lee, Cole, Johnstone, Levine, Zucker, Guenther, Kumar, Murray, Jenner, Gifford, Melton, Jaenisch, Young: "Core transcriptional regulatory circuitry in human embryonic stem cells." in: Cell, Vol. 122, Issue 6, pp. 947-56, (2005) (PubMed).

  • 抗原

    SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

    别名

    SOX2

    背景

    The monoclonal antibody O30-678 recognizes the Sox2 transcription factor. Sox2 [SRY (sex determining region Y)-box 2] is a member of the SRY-related HMG-box (SOX) family of transcription factors. Sox2 is required for the maintenance of the undifferentiated state of pluripotent stem cells. Complexes of Sox2 with the homeobox transcription factors Oct3/4 and/or Nanog bind to the promoters of a network of genes that are involved in the maintenance of pluripotency and self renewal in stem cells. Sox2 is also a marker of neural stem cells during embryonic development and in the adult brain. The O30-678 antibody recognizes both human and mouse Sox2 proteins.

    分子量

    36 kDa

    基因ID

    6657, 20674

    途径

    Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
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