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DPP4 抗体

DPP4 适用: 大鼠 FACS, WB, IHC (fro), IP 宿主: 小鼠 Monoclonal OX-61 unconjugated
产品编号 ABIN967645
发货至: 中国
  • 抗原 See all DPP4 抗体
    DPP4 (Dipeptidyl-Peptidase 4 (DPP4))
    适用
    • 131
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    大鼠
    宿主
    • 93
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    • 1
    小鼠
    克隆类型
    • 88
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    单克隆
    标记
    • 79
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    This DPP4 antibody is un-conjugated
    应用范围
    • 75
    • 68
    • 50
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    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)
    品牌
    BD Pharmingen™
    产品特性
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Sodium azide is a reversible inhibitor of oxidative metabolism, therefore, antibody preparations containing this preservative agent must not be used in cell cultures nor injected into animals. Sodium azide may be removed by washing stained cells or plate-bound antibody or dialyzing soluble antibody in sodium azide-free buffer. Since endotoxin may also affect the results of functional studies, we recommend the NA/LE (No Azide/Low Endotoxin) antibody format, if available, for in vitro and in vivo use.
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Rat dendritic cells enriched from thoracic duct lymph
    克隆位点
    OX-61
    亚型
    IgG2a kappa
    Top Product
    Discover our top product DPP4 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C.
  • Iwaki-Egawa, Watanabe, Fujimoto: "CD26/dipeptidyl peptidase IV does not work as an adenosine deaminase-binding protein in rat cells." in: Cellular immunology, Vol. 178, Issue 2, pp. 180-6, (1997) (PubMed).

    Johnson, Zhu, Augustin-Voss, Pauli: "Lung endothelial dipeptidyl peptidase IV is an adhesion molecule for lung-metastatic rat breast and prostate carcinoma cells." in: The Journal of cell biology, Vol. 121, Issue 6, pp. 1423-32, (1993) (PubMed).

    Kameoka, Tanaka, Nojima, Schlossman, Morimoto: "Direct association of adenosine deaminase with a T cell activation antigen, CD26." in: Science (New York, N.Y.), Vol. 261, Issue 5120, pp. 466-9, (1993) (PubMed).

    Bristol, Sakaguchi, Appella, Doyle, Takács: "Thymocyte costimulating antigen is CD26 (dipeptidyl-peptidase IV). Costimulation of granulocyte, macrophage, and T lineage cell proliferation via CD26." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 149, Issue 2, pp. 367-72, (1992) (PubMed).

    Gorrell, Wickson, McCaughan: "Expression of the rat CD26 antigen (dipeptidyl peptidase IV) on subpopulations of rat lymphocytes." in: Cellular immunology, Vol. 134, Issue 1, pp. 205-15, (1991) (PubMed).

    McCaughan, Wickson, Creswick, Gorrell: "Identification of the bile canalicular cell surface molecule GP110 as the ectopeptidase dipeptidyl peptidase IV: an analysis by tissue distribution, purification and N-terminal amino acid sequence." in: Hepatology (Baltimore, Md.), Vol. 11, Issue 4, pp. 534-44, (1990) (PubMed).

    Piazza, Callanan, Mowery, Hixson: "Evidence for a role of dipeptidyl peptidase IV in fibronectin-mediated interactions of hepatocytes with extracellular matrix." in: The Biochemical journal, Vol. 262, Issue 1, pp. 327-34, (1989) (PubMed).

    Hanski, Huhle, Gossrau, Reutter: "Direct evidence for the binding of rat liver DPP IV to collagen in vitro." in: Experimental cell research, Vol. 178, Issue 1, pp. 64-72, (1988) (PubMed).

  • 抗原
    DPP4 (Dipeptidyl-Peptidase 4 (DPP4))
    别名
    CD26 (DPP4 产品)
    别名
    ADABP antibody, ADCP2 antibody, CD26 antibody, DPPIV antibody, TP103 antibody, MGC81966 antibody, MOP9.8 antibody, MOP9_8 antibody, DPP4 antibody, si:ch73-2d23.3 antibody, Cd26 antibody, Dpp-4 antibody, THAM antibody, dipeptidyl peptidase 4 antibody, dipeptidyl-peptidase 4 S homeolog antibody, prolyl oligopeptidase family protein antibody, dipeptidyl-peptidase 4 antibody, dipeptidylpeptidase 4 antibody, DPP4 antibody, dpp4.S antibody, AT5G24260 antibody, dpp4 antibody, Dpp4 antibody
    背景
    The OX-61 antibody reacts with a type II transmembrane glycoprotein, CD26, which is a serine exoprotease identified as dipeptidyl/peptidase IV. Among various biological activities, rat CD26 binds fibronectin and collagen. Rat CD26 is involved in the costimulation of thymocyte proliferation in vitro, particularly the CD4-/CD8- subset, and is developmentally regulated on hematopoietic cells. Although mouse and human CD26 anchor ADA (adenosine deaminase) to cell membranes, rat CD26 does not function as an ADA-binding protein. Rat CD26 is expressed in lung endothelial cells, as well as in various epithelial cells. T cells express lower levels of CD26 than CD4-/CD8- thymocytes. The distribution of CD26 antigen in rat bone marrow cells is similar to that of human CD26. OX-61 monoclonal antibody stains CD4+, CD8+, and Ig+ lymphocytes, and the staining increases upon activation.
    途径
    Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity
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