(4 references)-
- 抗原 See all ITGB1 抗体
- ITGB1 (Integrin beta 1 (ITGB1))
-
适用
- 小鼠
-
宿主
- 大鼠
-
克隆类型
- 单克隆
-
标记
- This ITGB1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 品牌
- BD Pharmingen™
- 产品特性
-
1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- (C57BL/6 x DBA/2)F1 mouse bone-marrow stromal cell clone BMS2
- 克隆位点
- KMI6
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product ITGB1 Primary Antibody
-
anti-Integrin beta 1 (ITGB1) (AA 25-100) antibody
ITGB1 适用: 人, 小鼠, 大鼠, 绵羊, 兔 WB, FACS, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 1 (ITGB1) antibodyITGB1 适用: 人, 猴 WB, FACS, ELISA, IHC, DNA Mic 宿主: 小鼠 Monoclonal 3B6 unconjugated
anti-Integrin beta 1 (ITGB1) (AA 140-383) antibodyITGB1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 1 (ITGB1) antibodyITGB1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Integrin beta 1 (ITGB1) antibodyITGB1 适用: 人, Pig, 犬 WB, FACS, IP 宿主: 小鼠 Monoclonal MEM-101A unconjugated
anti-Integrin beta 1 (ITGB1) antibody (PE)ITGB1 适用: 人, Pig, 犬 FACS 宿主: 小鼠 Monoclonal MEM-101A PE
anti-Integrin beta 1 (ITGB1) (AA 297-380) antibodyITGB1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 1 (ITGB1) antibodyITGB1 适用: 人 WB, FACS, ELISA, IHC, IF 宿主: 兔 Monoclonal 32A10 unconjugated Recombinant Antibody
anti-Integrin beta 1 (ITGB1) (AA 454-714) antibodyITGB1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 1 (ITGB1) (AA 140-383) antibodyITGB1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C2 unconjugated
-
- 应用备注
- Please note that the epitope is lost upon sulfhydryl reduction of the antigen. For IHC, we recommend the use of purified anti-mouse CD29 mAb 9EG7 mAb in our special formulation for immunohistochemistry.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4° C.
-
-
: "Expression of a novel integrin beta 1 chain epitope and anti-beta 1 antibody-mediated enhancement of fibronectin binding are dependent on the stage of T cell differentiation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 5, pp. 2125-33, (1995) (PubMed).
: "Recognition of murine integrin beta 1 by a rat anti-stromal cell monoclonal antibody." in: Hybridoma, Vol. 13, Issue 5, pp. 409-16, (1995) (PubMed).
: "Highly restricted expression of a stromal cell determinant in mouse bone marrow in vivo." in: The Journal of experimental medicine, Vol. 176, Issue 4, pp. 927-35, (1992) (PubMed).
: "Adhesion receptors of the immune system." in: Nature, Vol. 346, Issue 6283, pp. 425-34, (1990) (PubMed).
-
: "Expression of a novel integrin beta 1 chain epitope and anti-beta 1 antibody-mediated enhancement of fibronectin binding are dependent on the stage of T cell differentiation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 5, pp. 2125-33, (1995) (PubMed).
-
- 抗原
- ITGB1 (Integrin beta 1 (ITGB1))
- 别名
- CD29 (ITGB1 产品)
- 别名
- CD29 antibody, FNRB antibody, GPIIA antibody, MDF2 antibody, MSK12 antibody, VLA-BETA antibody, VLAB antibody, 4633401G24Rik antibody, AA409975 antibody, AA960159 antibody, ENSMUSG00000051907 antibody, Fnrb antibody, Gm9863 antibody, gpIIa antibody, cd29 antibody, fnrb antibody, gpiia antibody, itgb1 antibody, mdf2 antibody, msk12 antibody, vla-beta antibody, vlab antibody, itgb1-a antibody, itgb1-b antibody, integrin subunit beta 1 antibody, integrin beta 1 (fibronectin receptor beta) antibody, integrin subunit beta 1 S homeolog antibody, integrin beta 1 antibody, integrin subunit beta 1 L homeolog antibody, ITGB1 antibody, Itgb1 antibody, itgb1.S antibody, LOC100009173 antibody, itgb1.L antibody
- 背景
-
The KMI6 antibody reacts with the 130-kDa integrin ß1 chain (CD29). CD29 is expressed on the cell surface as a heterodimer with one of the distinct integrin achains. With a1 through a6 (CD49a through CD49f), it forms the VLA-1 through VLA-6 complexes, respectively, and with av (CD51), it forms avß1 integrin. It also associates with the integrin a7, a8, and a9 chains in non-lymphoid tissues. As a result, CD29 has a broad tissue distribution, including leukocytes, endothelia, smooth muscle, epithelia, and oocytes. The epitope recognized by the KMI6 mAb can be detected by immunoblot in unreduced extracts from a variety of cells and tissues having a number of different ß1-integrin heterodimer combinations. However, the epitope is not well expressed on the surface of the majority of hematopoietic cells. It is detected on the surface of fetal liver cells, some bone marrow stromal cells, and some cultured hematopoietic cell lines, including P815 and PA6. Surface expression of the CD29 epitope recognized by mAb KMI6 on thymocytes and T lymphocytes appears to be developmentally regulated, and KMI6 antibody enhances the adhesion of KMI6 thymocytes to fibronectin and laminin.
Synonyms: Integrin beta1 chain - 途径
- Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome
-
You are here:
