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CD247 抗体 (AA 153-164)

Name: CD247 抗体 (AA 153-164)
SKU: ABIN967517
Availability: OutOfStock

This anti-CD247 antibody is a 小鼠单克隆 antibody detecting CD247 in WB 和 IP. Suitable for 人. This Primary Antibody has been cited in 3+ publications.

(3 references)

产品编号 ABIN967517

发货至: 中国

Quick Overview for CD247 抗体 (AA 153-164) (ABIN967517)

抗原

See all CD247 抗体

CD247 (CD247 Molecule (CD247))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This CD247 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunoprecipitation (IP)

克隆位点

1D4

Discover our top product CD247 Primary Antibody

抗原表位
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AA 153-164

品牌

BD Pharmingen™

产品特性

1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

纯化方法

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

免疫原

Human CD3zeta synthetic peptide aa. 153-164

亚型

IgG1
anti-CD247 Molecule (CD247) (pTyr72) antibody
CD247 适用: 人, 小鼠 WB, ICC, ICFC 宿主: 小鼠 Monoclonal EM-26 unconjugated

anti-CD247 Molecule (CD247) (AA 1-164) antibody
CD247 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-CD247 Molecule (CD247) (AA 1-164) antibody
CD247 适用: 人 WB, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal 4A12-F6 unconjugated

anti-CD247 Molecule (CD247) (AA 88-153) antibody
CD247 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-CD247 Molecule (CD247) (AA 50-164) antibody
CD247 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-CD247 Molecule (CD247) antibody
CD247 适用: 人 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 4B10 unconjugated

anti-CD247 Molecule (CD247) antibody
CD247 适用: 人 WB, IHC, FACS 宿主: 兔 Monoclonal unconjugated

anti-CD247 Molecule (CD247) (AA 1-165) antibody
CD247 适用: 人 WB, IP, IHC (p), EIA 宿主: 小鼠 Monoclonal 4A12-F6 unconjugated

anti-CD247 Molecule (CD247) (AA 51-100) antibody
CD247 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-CD247 Molecule (CD247) (C-Term) antibody
CD247 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Applications include immunoprecipitation and western blot analysis (1-2 µg/ml). Jurkat T cells (ATCC TIB 152) are suggested as a positive control.

限制

仅限研究用
状态

Liquid

浓度

0.5 mg/mL

缓冲液

Aqueous buffered solution containing ≤0.09 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C

储存方法

Store undiluted at 4°C.
Hall, Sancho, Terhorst: "Reconstitution of T cell receptor zeta-mediated calcium mobilization in nonlymphoid cells." in: Science (New York, N.Y.), Vol. 261, Issue 5123, pp. 915-8, (1993) (PubMed).

Hussey, Clayton, Diener, McConkey, Howard, Rodewald, DAdamio, Dallenbach, Stein, Schmidt: "Overexpression of CD3 eta during thymic development does not alter the negative selection process." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 150, Issue 4, pp. 1183-94, (1993) (PubMed).

Sancho, Franco, Chatila, Hall, Terhorst: "The T cell receptor associated CD3-epsilon protein is phosphorylated upon T cell activation in the two tyrosine residues of a conserved signal transduction motif." in: European journal of immunology, Vol. 23, Issue 7, pp. 1636-42, (1993) (PubMed).
抗原

CD247 (CD247 Molecule (CD247))

别名

CD247

背景

The T-cell receptor (TCR), expressed by thymus-derived lymphocytes, is a multicomponent complex responsible for recognizing antigen in the context of MHC molecules. Ti is the antigen-specific binding component of the TCR. On the majority of peripheral T lymphocytes Ti is present as a disulfide-linked alpha-beta heterodimer. A minor fraction express Ti as a gamma-delta heterodimer. The Ti subunits are Ig-like, each containing V and C regions. Ti is noncovalently associated with an invariant set of molecules referred to as the CD3 subunits. CD3 appears early in thymocyte differentiation and remains expressed on all mature T lymphocytes. In the mouse, it consists of five chains, gamma (gamma), delta (delta), epsilon (epsilon), zeta (zeta), and p21. The relative masses of the mouse CD3 chains are 21, 28, 26, 32, (dimer), and 21 kD respectively. 1D4 recognizes human but not mouse CD3zeta. It is most efficient at recognizing the phosphorylated form of CD3zeta (21 kD) but will also bind the 16 kD unphosphorylated monomer as well as higher molecular weight dimers. A synthetic peptide corresponding to amino acids 153 to 164 of human CD3zeta was used as immunogen.
Synonyms: CD3zeta chain

分子量

21 kDa

途径

TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway