MYOD1 抗体
(5 references)Quick Overview for MYOD1 抗体 (ABIN967403)
抗原
See all MYOD1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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品牌
- BD Pharmingen™
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交叉反应
- 人, 大鼠, 小鸡
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产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Recombinant Mouse MyoD
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亚型
- IgG1 kappa
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anti-Myogenic Differentiation 1 (MYOD1) (AA 150-250) antibody
MYOD1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Myogenic Differentiation 1 (MYOD1) (AA 51-150) antibodyMYOD1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Myogenic Differentiation 1 (MYOD1) antibodyMYOD1 适用: 人 IHC, StM 宿主: 兔 Monoclonal MYOD1-2075R unconjugated Recombinant Antibody
anti-Myogenic Differentiation 1 (MYOD1) antibodyMYOD1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rMYD712 unconjugated Recombinant Antibody
anti-Myogenic Differentiation 1 (MYOD1) (AA 1-320) antibodyMYOD1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myogenic Differentiation 1 (MYOD1) antibodyMYOD1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Myogenic Differentiation 1 (MYOD1) (AA 211-320) antibodyMYOD1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Myogenic Differentiation 1 (MYOD1) (AA 1-320) antibodyMYOD1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Myogenic Differentiation 1 (MYOD1) (AA 211-320) antibodyMYOD1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A7 unconjugated
anti-Myogenic Differentiation 1 (MYOD1) (AA 211-240) antibodyMYOD1 适用: 人 WB, IF, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4° C.
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: "Overlapping functions of the myogenic bHLH genes MRF4 and MyoD revealed in double mutant mice." in: Development (Cambridge, England), Vol. 125, Issue 13, pp. 2349-58, (1998) (PubMed).
: "Mitogen-activated protein kinase pathway is involved in the differentiation of muscle cells." in: The Journal of biological chemistry, Vol. 273, Issue 17, pp. 10436-44, (1998) (PubMed).
: "The molecular basis of skeletal muscle differentiation." in: Seminars in diagnostic pathology, Vol. 11, Issue 1, pp. 3-14, (1994) (PubMed).
: "Monoclonal antibodies to the myogenic regulatory protein MyoD1: epitope mapping and diagnostic utility." in: Cancer research, Vol. 52, Issue 23, pp. 6431-9, (1992) (PubMed).
: "Expression of a single transfected cDNA converts fibroblasts to myoblasts." in: Cell, Vol. 51, Issue 6, pp. 987-1000, (1988) (PubMed).
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: "Overlapping functions of the myogenic bHLH genes MRF4 and MyoD revealed in double mutant mice." in: Development (Cambridge, England), Vol. 125, Issue 13, pp. 2349-58, (1998) (PubMed).
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- MYOD1 (Myogenic Differentiation 1 (MYOD1))
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别名
- MyoD
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背景
- MyoD is a member of a family of myogenic basic helix-loop-helix (bHLH) transcription factors that includes Myf-5, myogenin, and MRF4 (also known as herculin or Myf-6). Members of this family, expressed exclusively in skeletal muscle, play a key role in myogenesis by activating muscle-specific genes in response to extracellular growth factors. Transfection of MyoD and other family members into non-muscle cells has been shown to either convert these cells to myogenic cells or to transcriptionally activate a set of otherwise unexpressed muscle-specific genes. Members of this family have distinct roles in muscle development, for example, MyoD and Myf-5 act early during myeloid development, whereas myogenin acts at a later point during myoblast differentiation. The expression and activity of MyoD has been shown to involve the mitogen-activated protein kinase (MAPK) cascade. This antibody is routinely tested by western blot analysis. The epitope for MoAb 5.8A has been mapped to amino acids 180-189nof mouse MyoD.
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分子量
- 45/48 kDa
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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