Panendothelial Cell 抗体
There are 6+ publications for this product available. The 大鼠 单克隆 anti-Panendothelial Cell antibody is suitable to detect Panendothelial Cell in samples from 小鼠. It has been validated for IHC (fro), FACS, IP 和 WB.
(6 references)
产品编号 ABIN967385
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Panendothelial Cell 抗体 (ABIN967385)
抗原
Panendothelial Cell
适用
小鼠
宿主
大鼠
克隆类型
单克隆
应用范围
Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)
克隆位点
MECA-32
-
-
产品特性
-
1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
-
免疫原
- Mouse lymph node stromal cells
-
亚型
- IgG2a kappa
-
-
-
应用备注
- For IHC, we recommend the use of purified MECA-32 mAb in our special formulation for immunohistochemistry.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Store undiluted at 4° C.
-
-
-
: "Novel mouse endothelial cell surface marker is suppressed during differentiation of the blood brain barrier." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 202, Issue 4, pp. 325-32, (1995) (PubMed).
: "Treatment of mice with anti-CD3 mAb induces endothelial vascular cell adhesion molecule-1 expression." in: Transplantation, Vol. 57, Issue 5, pp. 711-7, (1994) (PubMed).
: "Cell adhesion molecules on vessels during inflammation in the mouse central nervous system." in: Journal of neuroimmunology, Vol. 51, Issue 2, pp. 199-208, (1994) (PubMed).
: "Dissecting the hematopoietic microenvironment. IX. Further characterization of murine bone marrow stromal cells." in: Blood, Vol. 81, Issue 5, pp. 1205-13, (1993) (PubMed).
: "Role of the endothelial adhesion molecule VCAM in murine cardiac allograft rejection." in: Immunology letters, Vol. 32, Issue 1, pp. 7-12, (1992) (PubMed).
: "Inducible expression of an endothelial cell antigen on murine myocardial vasculature in association with interstitial cellular infiltration." in: Transplantation, Vol. 48, Issue 5, pp. 874-7, (1989) (PubMed).
-
-
- Panendothelial Cell
-
背景
- The MECA-32 antibody reacts with a dimer of 50-55-kDa subunits expressed on most or all endothelial cells in the embryonic and adult mouse, with the exception of cardiac and skeletal muscle and the brain. Normally in skeletal and cardiac muscle, MECA-32 antigen expression is limited to small arterioles and venules, however, under conditions of inflammation, it can be induced on previously non-expressing vessels in cardiac muscle. In the central nervous system (CNS), the panendothelial cell antigen expression is developmentally regulated. During embryonic development, the antigen is found on brain vasculature up to day 16 of gestation, after which it disappears. The cessation of MECA-32 antigen expression in the CNS may be associated with the establishment of the blood-brain barrier, which begins on day 16 of gestation. In the adult mouse, inflammation in the CNS can lead to re-expression of the panendothelial cell antigen.
抗原
-
You are here:
