Integrin beta 4 抗体
(7 references)-
- 抗原 See all Integrin beta 4 (ITGB4) 抗体
- Integrin beta 4 (ITGB4)
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This Integrin beta 4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 品牌
- BD Pharmingen™
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Sodium azide is a reversible inhibitor of oxidative metabolism, therefore, antibody preparations containing this preservative agent must not be used in cell cultures nor injected into animals. Sodium azide may be removed by washing stained cells or plate-bound antibody or dialyzing soluble antibody in sodium azide-free buffer. Since endotoxin may also affect the results of functional studies, we recommend the NA/LE (No Azide/Low Endotoxin) antibody format, if available, for in vitro and in vivo use. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Tumor-associated antigen TSP-180 from a BALB/c mouse lung carcinoma
- 克隆位点
- 346-11A
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product ITGB4 Primary Antibody
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anti-Integrin beta 4 (ITGB4) (AA 1619-1822) antibody
ITGB4 适用: 人 WB, IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 10B10D5 unconjugated
anti-Integrin beta 4 (ITGB4) (AA 29-206) antibodyITGB4 适用: 人 WB, IHC, FACS, ELISA, ICC, Neut 宿主: 小鼠 Monoclonal 5G3G5 unconjugated
anti-Integrin beta 4 (ITGB4) (AA 1401-1533) antibodyITGB4 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) (C-Term) antibodyITGB4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) (AA 28-310) antibodyITGB4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) (Tyr1510) antibodyITGB4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) (AA 28-137) antibodyITGB4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) antibodyITGB4 适用: 人 WB, ELISA, ICC 宿主: 小鼠 Monoclonal M126 unconjugated
anti-Integrin beta 4 (ITGB4) (pTyr1494) antibodyITGB4 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) (pTyr1526) antibodyITGB4 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4° C.
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: "Expression of the beta 4 integrin subunit induces monocytic differentiation of 32D/v-Abl cells." in: Blood, Vol. 100, Issue 1, pp. 96-106, (2002) (PubMed).
: "Signal transduction by the alpha 6 beta 4 integrin: charting the path between laminin binding and nuclear events." in: Journal of cell science, Vol. 109 ( Pt 6), pp. 1165-72, (1997) (PubMed).
: "Epithelial detachment due to absence of hemidesmosomes in integrin beta 4 null mice." in: Nature genetics, Vol. 13, Issue 3, pp. 366-9, (1996) (PubMed).
: "Integrin alpha 6/beta 4 complex is located in hemidesmosomes, suggesting a major role in epidermal cell-basement membrane adhesion." in: The Journal of cell biology, Vol. 113, Issue 4, pp. 907-17, (1991) (PubMed).
: "The alpha 6 beta 1 (VLA-6) and alpha 6 beta 4 protein complexes: tissue distribution and biochemical properties." in: Journal of cell science, Vol. 96 ( Pt 2), pp. 207-17, (1990) (PubMed).
: "Analysis of the tumor-associated antigen TSP-180. Identity with alpha 6-beta 4 in the integrin superfamily." in: The Journal of biological chemistry, Vol. 264, Issue 26, pp. 15515-21, (1989) (PubMed).
: "Tumor antigen on benign adenomas and on murine lung carcinomas quantitated by a two-site monoclonal antibody assay." in: Cancer research, Vol. 46, Issue 2, pp. 707-12, (1986) (PubMed).
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: "Expression of the beta 4 integrin subunit induces monocytic differentiation of 32D/v-Abl cells." in: Blood, Vol. 100, Issue 1, pp. 96-106, (2002) (PubMed).
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- 抗原
- Integrin beta 4 (ITGB4)
- 别名
- CD104 (ITGB4 产品)
- 别名
- AA407042 antibody, C230078O20 antibody, CD104 antibody, integrin subunit beta 4 antibody, integrin beta 4 antibody, ITGB4 antibody, Itgb4 antibody
- 背景
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The 346-11A antibody reacts with an epitope at the beginning of the cysteine-rich repeat region of the 200-kDa integrin beta4 chain (CD104), which is found on the cell surface as a heterodimeric complex with the integrin alpha6 chain (CD49f). The alpha6beta4 complex binds to laminins and is expressed on the basal surface of a variety of epithelial cell types, particularly on stratified squamous epithelia, and is also found in peripheral nerves, in certain subsets of endothelial cells, and on immature thymocytes. It has also been identified on a number of tumor tissues and participates in tumor progression events. Because of the localization of both human and mouse epidermal alpha6beta4 integrin to hemidesmosomes, a role in epidermal adhesion to basement membrane has been suggested.
Synonyms: Integrin beta4 chain - 途径
- Integrin Complex
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